Gene: ERI1
Official Full Name: exoribonuclease 1provided by HGNC
Gene Summary: Enables 3'-5' exonuclease activity. Involved in maturation of 5.8S rRNA. Located in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23744 | ERI1 Knockout cell line (HeLa) | Human | ERI1 | 1:3~1:6 | Negative | Online Inquiry |
KO23745 | ERI1 Knockout cell line (HCT 116) | Human | ERI1 | 1:2~1:4 | Negative | Online Inquiry |
KO23746 | ERI1 Knockout cell line (HEK293) | Human | ERI1 | 1:3~1:6 | Negative | Online Inquiry |
KO23747 | ERI1 Knockout cell line (A549) | Human | ERI1 | 1:3~1:4 | Negative | Online Inquiry |
ERI1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the ERI1 gene, which is involved in RNA processing and the regulation of gene expression. These knockout cell lines are meticulously created using CRISPR/Cas9 technology, allowing for precise gene disruptions that facilitate the study of gene function, cellular pathways, and disease mechanisms. The removal of ERI1 enables researchers to gain insights into its role in mRNA decay and innate immune responses, as well as its implications in various cancers and developmental disorders.
The key function of ERI1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for discerning the gene's impact on cellular behavior. By comparing these knockout lines with wild-type controls, scientists can observe variations in cellular proliferation, differentiation, and response to stressors, thereby elucidating the downstream effects of ERI1 absence. This makes them invaluable tools for both basic and translational research, helping to uncover molecular pathways and potential therapeutic targets.
In research and clinical settings, the significance of ERI1 knockout models extends to drug development, biomarker discovery, and gene function studies. By facilitating the dissection of complex biological processes, these cell lines can accelerate the identification of novel treatment strategies for diseases related to ERI1 dysregulation.
Compared to other gene knockout models, ERI1 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility. Their design allows for quick adaptation into various experimental paradigms, enhancing the speed at which results can be generated. Moreover, the CRISPR technology underlying their construction ensures that off-target effects are minimized, providing researchers with confidence in their findings.
For researchers, clinicians, and biopharmaceutical companies, the value of ERI1 Gene Knockout Cell Lines lies in their potential to advance knowledge and innovation in gene function and therapeutic interventions. These models not only serve as powerful experimental systems but also represent a cornerstone for future discoveries in molecular biology.
As a company committed to excellence in biological research tools, we take pride in our expertise in genetic engineering and cell line development, ensuring that our products are backed by rigorous scientific validation and quality assurance. Our ERI1 Gene Knockout Cell Lines exemplify this commitment and are a testament to our dedication to empowering researchers in their pursuit of scientific breakthroughs.
Please note that all services are for research use only. Not intended for any clinical use.
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