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ERGIC2 Knockout Cell Lines

Gene: ERGIC2

Official Full Name: ERGIC and golgi 2provided by HGNC

Gene Summary: ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22739 ERGIC2 Knockout cell line (HeLa) Human ERGIC2 1:3~1:6 Negative Online Inquiry
KO22740 ERGIC2 Knockout cell line (HCT 116) Human ERGIC2 1:2~1:4 Negative Online Inquiry
KO22741 ERGIC2 Knockout cell line (HEK293) Human ERGIC2 1:3~1:6 Negative Online Inquiry
KO22742 ERGIC2 Knockout cell line (A549) Human ERGIC2 1:3~1:4 Negative Online Inquiry

Background

The ERGIC2 Gene Knockout Cell Lines represent a cutting-edge tool in cellular biology research, providing researchers with a unique model to study the functional implications of the ERGIC2 gene. This gene is involved in the early secretory pathway and is critical for the proper functioning of the endoplasmic reticulum–Golgi intermediate compartment. By employing CRISPR-Cas9 gene editing technology, these cell lines are engineered to have a complete knockout of the ERGIC2 gene, enabling detailed analysis of its role in cellular processes such as protein trafficking, cellular stress responses, and membrane dynamics.

The primary function of ERGIC2 is to facilitate the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. In the context of these knockout cell lines, researchers can observe and quantify subsequent changes in protein distribution and secretory pathway dynamics, offering insights into the mechanisms underlying various cellular processes and disease states. The utility of these cell lines extends into clinical research, where understanding the ERGIC2 gene's role can illuminate potential therapeutic targets for conditions such as neurodegenerative diseases and certain cancers.

Compared to existing alternatives, the ERGIC2 Gene Knockout Cell Lines offer unparalleled specificity and reliability, minimizing off-target effects commonly associated with other gene-editing technologies. This specificity enables researchers to draw clearer conclusions from their experiments, enhancing the overall robustness of scientific findings. Additionally, the versatility of these cell lines allows for application in various model systems, making them an indispensable asset across different research disciplines.

For researchers and clinicians aiming to bridge the gap between basic and applied science, the ERGIC2 Gene Knockout Cell Lines present an invaluable resource that can propel understanding and innovation. With years of expertise in producing high-quality biological products, our company is committed to supporting the scientific community with tools that facilitate groundbreaking discoveries and advance human health.

Please note that all services are for research use only. Not intended for any clinical use.

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