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EPS15L1 Knockout Cell Lines

Gene: EPS15L1

Official Full Name: epidermal growth factor receptor pathway substrate 15 like 1provided by HGNC

Gene Summary: Enables cadherin binding activity. Predicted to be involved in endosomal transport and synaptic vesicle endocytosis. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17926 EPS15L1 Knockout cell line (HeLa) Human EPS15L1 1:3~1:6 Negative Online Inquiry
KO17927 EPS15L1 Knockout cell line (HCT 116) Human EPS15L1 1:2~1:4 Negative Online Inquiry
KO17928 EPS15L1 Knockout cell line (HEK293) Human EPS15L1 1:3~1:6 Negative Online Inquiry
KO17929 EPS15L1 Knockout cell line (A549) Human EPS15L1 1:3~1:4 Negative Online Inquiry

Background

EPS15L1 Gene Knockout Cell Lines are specifically engineered cellular models that lack the expression of the EPS15L1 gene, which encodes a protein pivotal in endocytosis and intracellular signaling pathways. These knockout cell lines are generated through precise genetic modifications, using techniques such as CRISPR/Cas9 or RNA interference, to create a robust platform for studying the physiological and pathological roles of EPS15L1 in various biological contexts.

The primary function of these cell lines is to facilitate the exploration of signal transduction and membrane dynamics, particularly in the context of cancer biology and receptor-mediated endocytosis. By examining the growth, migration, and interaction of EPS15L1-deficient cells, researchers can gain insights into how the loss of this gene may influence tumorigenesis or affect response to therapy. As such, these cell lines serve as valuable tools in elucidating the underlying mechanisms of many diseases linked to abnormal cellular signaling.

In research and clinical settings, EPS15L1 Gene Knockout Cell Lines hold significant importance for drug development and therapeutic target validation. They allow scientists to dissect the role of EPS15L1 in various cellular processes and evaluate potential machinations for novel pharmacological interventions. Their availability supports both basic research and translational endeavors, giving researchers insights that may lead to the design of more targeted treatment strategies.

Compared to alternative models, EPS15L1 Gene Knockout Cell Lines provide enhanced specificity in the study of gene function. Unlike traditional knockdown methods that may produce incomplete silencing, these knockout lines allow for a complete loss of function, yielding clearer interpretations of gene action. Additionally, their ease of use and straightforward integration into existing workflows make them an attractive choice for investigators.

For researchers and clinicians seeking to unravel complex biological questions surrounding cellular dynamics, the EPS15L1 Gene Knockout Cell Lines represent a powerful asset. By leveraging this innovative tool, users can accelerate their understanding of disease mechanisms and potential therapeutic avenues.

As a leading provider of cutting-edge biological products, our commitment ensures that each EPS15L1 Gene Knockout Cell Line meets rigorous quality standards, helping you advance your research endeavors with precision and confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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