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EPHA6 Knockout Cell Lines

Gene: EPHA6

Official Full Name: EPH receptor A6provided by HGNC

Gene Summary: Predicted to enable transmembrane-ephrin receptor activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35616 EPHA6 Knockout cell line (HeLa) Human EPHA6 1:3~1:6 Negative Online Inquiry
KO35617 EPHA6 Knockout cell line (HEK293) Human EPHA6 1:3~1:6 Negative Online Inquiry

Background

EPHA6 Gene Knockout Cell Lines are specialized genetic models designed to study the EPHA6 gene's functions by creating a complete loss-of-function scenario. EPHA6, a member of the Ephrin receptor family, plays a critical role in various cellular processes, including neuronal development, cellular migration, and synaptic plasticity. The gene knockout technique involves targeted gene disruption, enabling researchers to observe the resultant phenotypic changes and cellular pathways affected by the absence of EPHA6.

These cell lines facilitate in-depth exploration of the mechanisms underlying EPHA6’s contribution to neuronal signaling and its implications in neurodevelopmental disorders. By analyzing these knockout cell lines, researchers can clarify EPHA6's involvement in critical physiological processes and uncover potential pathological links to diseases such as autism spectrum disorders and other neurodegenerative conditions. This makes the EPHA6 Gene Knockout Cell Lines invaluable for both foundational research and translational studies aiming to develop targeted therapies.

Compared to alternative models, the knockout cell lines provide a precise and efficient means of studying gene function without the confounding effects of a partially functional gene product. Additionally, these models can be coupled with high-throughput screening and CRISPR technology for enhanced application flexibility.

Researchers and clinicians focused on neurobiology and genetics will particularly benefit from using EPHA6 Gene Knockout Cell Lines, as they offer the opportunity to dissect complex signaling networks with unprecedented clarity. Our company specializes in providing high-quality, validated genetic tools designed by experts in molecular biology, ensuring that users have access to reliable products that enhance their research capabilities and outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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