Gene: EPB41
Official Full Name: erythrocyte membrane protein band 4.1provided by HGNC
Gene Summary: The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38006 | EPB41 Knockout cell line (HeLa) | Human | EPB41 | 1:3~1:6 | Negative | Online Inquiry |
KO38007 | EPB41 Knockout cell line (HCT 116) | Human | EPB41 | 1:2~1:4 | Negative | Online Inquiry |
KO38008 | EPB41 Knockout cell line (HEK293) | Human | EPB41 | 1:3~1:6 | Negative | Online Inquiry |
KO38009 | EPB41 Knockout cell line (A549) | Human | EPB41 | 1:3~1:4 | Negative | Online Inquiry |
EPB41 Gene Knockout Cell Lines are precisely engineered cellular models developed to study the functional consequences of the EPB41 gene's absence. EPB41 encodes a membrane-associated protein involved in various cellular functions, particularly in cytoskeletal organization and membrane stabilization. These knockout cell lines are created using advanced CRISPR-Cas9 technology, which ensures targeted disruption of the EPB41 gene. This results in a reliable and reproducible cellular model to investigate the biological roles and pathological implications of EPB41 loss.
The primary function of EPB41 Gene Knockout Cell Lines lies in their ability to facilitate detailed studies of cell morphology, adhesion, and migration, which are critical in understanding cellular responses in both normal physiological and disease contexts, such as cancer metastasis or hereditary disorders. The precise knockout of EPB41 allows researchers to elucidate the gene’s contributions to cellular homeostasis and its impact on signaling pathways, thereby advancing our knowledge in fields like developmental biology, tumor biology, and regenerative medicine.
In comparison to traditional cell lines, these knockout models present a significant advantage by minimizing the genetic variability typically observed in non-targeted cell lines. This high specificity enhances the reliability of results, making them invaluable tools for both research and clinical development settings. Researchers can confidently draw conclusions about the role of EPB41 in various processes, while clinicians can leverage these insights for potential therapeutic interventions.
Our company is committed to providing top-tier biological products, with a focus on delivering high-quality knockout cell lines. Our expert team is dedicated to supporting the needs of researchers and clinicians by offering products that enhance scientific inquiry and accelerate discovery, thus ensuring a shared goal of advancing health and understanding through precise genetic tools.
Please note that all services are for research use only. Not intended for any clinical use.
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