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ENTREP1 Knockout Cell Lines

Gene: ENTREP1

Official Full Name: endosomal transmembrane epsin interactor 1provided by HGNC

Gene Summary: Enables ubiquitin ligase activator activity. Involved in CXCL12-activated CXCR4 signaling pathway and negative adaptation of signaling pathway. Located in endosome membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17971 ENTREP1 Knockout cell line (HeLa) Human ENTREP1 1:3~1:6 Negative Online Inquiry
KO17972 ENTREP1 Knockout cell line (HCT 116) Human ENTREP1 1:2~1:4 Negative Online Inquiry
KO17973 ENTREP1 Knockout cell line (HEK293) Human ENTREP1 1:3~1:6 Negative Online Inquiry
KO17974 ENTREP1 Knockout cell line (A549) Human ENTREP1 1:3~1:4 Negative Online Inquiry

Background

ENTREP1 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional role of the ENTREP1 gene, which is implicated in various biological processes related to cellular metabolism and stress response. These cell lines are generated through advanced CRISPR-Cas9 technology, allowing for precise deletion of the ENTREP1 gene, thereby enabling researchers to observe subsequent phenotypic changes and elucidate the gene's contributions to cellular functions.

The key functions of ENTREP1 Gene Knockout Cell Lines include the assessment of gene expression regulation, understanding metabolic pathways, and contributing to drug discovery efforts aimed at targeting metabolic disorders. The absence of the ENTREP1 gene provides researchers with a controlled environment to analyze alterations in cellular behavior—such as changes in proliferation, differentiation, and response to external stressors. This can be especially valuable in investigating the mechanisms of diseases like cancer, where ENTREP1 may play a significant role.

Scientifically, these cell lines hold immense importance in both research and clinical settings. They serve as crucial tools for functional genomics studies and have applications in developing targeted therapies or understanding disease mechanisms at the molecular level. Furthermore, ENTREP1 Gene Knockout Cell Lines offer a platform for high-throughput screening of potential therapeutic compounds, contributing to the advancement of personalized medicine.

In comparison to alternative models, such as wild-type cell lines, the unique selling point of ENTREP1 Gene Knockout Cell Lines lies in their specificity and utility in gene function elucidation, which is often less reliably achieved in traditional models. The precise gene editing ensures reproducibility, making these cell lines invaluable for consistency in research outcomes.

For researchers and clinicians dedicated to exploring gene-function relationships and developing innovative therapeutic strategies, ENTREP1 Gene Knockout Cell Lines present a significant asset. By leveraging these models, users can attain deeper insights into the biochemical pathways influenced by the ENTREP1 gene, ultimately paving the way for breakthroughs in genetic research and therapeutic interventions.

Our company specializes in providing high-quality, reliable gene editing tools and cell lines, ensuring that scientists have the resources they need to contribute to the evolving landscape of molecular biology and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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