Gene: ENPP5
Official Full Name: ectonucleotide pyrophosphatase/phosphodiesterase family member 5provided by HGNC
Gene Summary: This gene encodes a type-I transmembrane glycoprotein. Studies in rat suggest the encoded protein may play a role in neuronal cell communications. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17979 | ENPP5 Knockout cell line (HCT 116) | Human | ENPP5 | 1:2~1:4 | Negative | Online Inquiry |
KO17980 | ENPP5 Knockout cell line (HEK293) | Human | ENPP5 | 1:3~1:6 | Negative | Online Inquiry |
ENPP5 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the ecto-nucleotide pyrophosphatase/phosphodiesterase 5 (ENPP5) gene. This gene encodes an enzyme that has been implicated in various biological processes, including nucleotide metabolism and cell signaling pathways. The resulting knockout cell lines serve as powerful tools for dissecting the functional consequences of ENPP5 deficiency in both in vitro and in vivo systems.
These cell lines operate through the precise modification of the cellular genome, leading to the absence of ENPP5 protein and associated pathways. By removing this critical enzyme, researchers can study the downstream effects on cellular activities such as proliferation, apoptosis, and responses to other signaling molecules. This elucidation of ENPP5's role enhances our understanding of its contributions to physiological and pathological states, particularly in conditions like cancer, cardiovascular diseases, and metabolic disorders.
The scientific significance of ENPP5 Gene Knockout Cell Lines lies in their application in both research and clinical settings. They are invaluable for functional genomics studies aimed at characterizing gene functions, drug discovery efforts targeting nucleotide metabolism, and therapeutic explorations in gene therapy approaches. Such cell lines provide an advanced model system for screening potential inhibitors or activators of the ENPP5 pathway.
One of the key advantages of our ENPP5 Gene Knockout Cell Lines is their reliability and reproducibility compared to traditional models. These lines are rigorously validated and come with optimized culture conditions, ensuring consistency across experiments. Additionally, they are available in several relevant cell types, allowing for tailored research approaches depending on specific cellular contexts.
For researchers and clinicians focused on unlocking the genetic and molecular underpinnings of various diseases, our ENPP5 Gene Knockout Cell Lines offer a unique opportunity to advance understanding and therapeutic interventions. With a strong commitment to quality and innovation, our company prides itself on providing high-fidelity biological products that catalyze groundbreaking discoveries in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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