Gene: ENGASE
Official Full Name: endo-beta-N-acetylglucosaminidaseprovided by HGNC
Gene Summary: This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. [provided by RefSeq, Feb 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17996 | ENGASE Knockout cell line (HeLa) | Human | ENGASE | 1:3~1:6 | Negative | Online Inquiry |
KO17997 | ENGASE Knockout cell line (HCT 116) | Human | ENGASE | 1:2~1:4 | Negative | Online Inquiry |
KO17998 | ENGASE Knockout cell line (HEK293) | Human | ENGASE | 1:3~1:6 | Negative | Online Inquiry |
KO17999 | ENGASE Knockout cell line (A549) | Human | ENGASE | 1:3~1:4 | Negative | Online Inquiry |
ENGASE Gene Knockout Cell Lines are a state-of-the-art tool designed for the precise manipulation of gene function in mammalian cells through advanced genome editing technology. These cell lines are engineered to ablate specific gene expressions, allowing researchers to investigate gene functions and their contributions to various biological processes and diseases. By employing techniques such as CRISPR-Cas9 or homologous recombination, ENGASE cell lines provide a robust platform for creating knockout models that reflect the loss-of-function phenotypes critical to understanding cellular mechanisms.
The key functionality of ENGASE Gene Knockout Cell Lines lies in their ability to facilitate targeted gene disruption, enabling extensive studies into protein functions, signaling pathways, and metabolic processes. By creating specific gene knockouts, researchers can elucidate the roles of individual genes in health and disease, leading to enhanced understanding of complex biological systems. This functionality is particularly valuable in pharmacology, toxicology, and cancer research, where elucidating the role of specific genes in therapeutic responses can inform future drug development.
In a clinical or research context, these cell lines provide significant advantages over traditional methods, such as RNA interference or chemical inhibitors, which may produce off-target effects or transient suppression. ENGASE cell lines are also compatible with high-throughput screening processes, making them suitable for large-scale drug discovery efforts. Additionally, their reproducibility and stability render them highly reliable for longitudinal studies.
Researchers and clinicians benefit from using ENGASE Gene Knockout Cell Lines as they represent an efficient and reliable tool to explore gene functions and potential therapeutic targets. The insights gained from studying these models can lead to innovative treatment strategies and a deeper understanding of molecular pathogenesis.
With a commitment to advancing genetic research, our company combines cutting-edge technology with expert scientific knowledge, providing products that empower the global research community in their quest to unlock the complexities of biological systems. ENGASE Gene Knockout Cell Lines are a testament to our dedication to delivering high-quality, innovative tools that facilitate groundbreaking research.
Please note that all services are for research use only. Not intended for any clinical use.
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