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ENAH Knockout Cell Lines

Gene: ENAH

Official Full Name: ENAH actin regulatorprovided by HGNC

Gene Summary: This gene encodes a member of the enabled/ vasodilator-stimulated phosphoprotein. Members of this gene family are involved in actin-based motility. This protein is involved in regulating the assembly of actin filaments and modulates cell adhesion and motility. Alternate splice variants of this gene have been correlated with tumor invasiveness in certain tissues and these variants may serve as prognostic markers. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08702 ENAH Knockout cell line (HeLa) Human ENAH 1:3~1:6 Negative Online Inquiry
KO08703 ENAH Knockout cell line (HCT 116) Human ENAH 1:2~1:4 Negative Online Inquiry
KO08704 ENAH Knockout cell line (HEK293) Human ENAH 1:3~1:6 Negative Online Inquiry
KO08705 ENAH Knockout cell line (A549) Human ENAH 1:3~1:4 Negative Online Inquiry

Background

ENAH Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the ENAH gene's role in various biological processes. By utilizing CRISPR/Cas9 technology, these cell lines have been engineered to eliminate the expression of the ENAH gene, allowing researchers to investigate its function and contributions to cell motility, morphology, and signal transduction pathways without the confounding effects of the gene's activity.

The core mechanism behind the function of ENAH Gene Knockout Cell Lines lies in their ability to provide a controlled environment where researchers can evaluate the consequences of the gene's absence on cellular behaviors. The knockout allows for the assessment of downstream signaling pathways affected by ENAH, as well as the analysis of phenotypic changes in cellular migration and adhesion. This model is particularly significant in cancer research, where understanding the invasive characteristics that ENAH may regulate is crucial for developing therapeutic strategies.

In comparison to conventional cell lines that do not permit targeted manipulations, ENAH Gene Knockout Cell Lines offer a distinct advantage. They provide a clearer insight into the gene's specific roles and allow for precise experimental designs that are otherwise hampered by genetic variability. Furthermore, these knockout lines can be used to screen new compounds, aiding in the identification of potential drugs that can modulate ENAH-related pathways.

For researchers and clinicians, the value of ENAH Gene Knockout Cell Lines lies in their ability to deliver reproducible and relevant data concerning gene function. This can propel advancements in understanding diseases where ENAH plays a role, thus facilitating the exploration of innovative therapeutic avenues. Given the rising importance of gene-targeted studies in biomedical research, the adoption of these cell lines could significantly expedite progress in various fields, from basic biology to clinical applications.

Our company leverages advanced genomic technologies and expertise in molecular biology to develop these cutting-edge research tools. We are committed to providing high-quality, well-characterized biological products that empower scientists in their quest for discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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