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EMD Knockout Cell Lines

Gene: EMD

Official Full Name: emerinprovided by HGNC

Gene Summary: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02595 EMD Knockout cell line (HeLa) Human EMD 1:3~1:6 Negative Online Inquiry
KO02596 EMD Knockout cell line (HCT 116) Human EMD 1:2~1:4 Negative Online Inquiry
KO02597 EMD Knockout cell line (HEK293) Human EMD 1:3~1:6 Negative Online Inquiry
KO02598 EMD Knockout cell line (A549) Human EMD 1:3~1:4 Negative Online Inquiry

Background

EMD Gene Knockout Cell Lines are specialized cellular models engineered to lack specific genes of interest, allowing researchers to study gene function and disease mechanisms in a controlled environment. These cell lines are generated using precise gene editing technologies such as CRISPR-Cas9, which enable targeted deletions that facilitate the investigation of cellular processes and pathways affected by the absent gene.

The key functions of EMD Gene Knockout Cell Lines revolve around their ability to provide insights into gene regulation, protein interactions, and signal transduction pathways. By employing these knockout models, researchers can observe the resulting phenotypic changes, enhance understanding of gene-related diseases, and screen for potential therapeutic targets. This mechanism of using gene editing to create functional gene loss is crucial for elucidating the biological roles of genes in various contexts, ranging from basic research to drug discovery.

Scientifically, the importance of EMD Gene Knockout Cell Lines is underscored by their wide applications across molecular biology, pharmacology, and genetic research. These models are invaluable for developing novel treatments, understanding cancer biology, and investigating genetic disorders.

When compared to alternative methods, such as siRNA-mediated knockdown, EMD Gene Knockout Cell Lines provide a more stable and permanent gene disruption, allowing for long-term studies without the confounding effects of transient knockdowns. This offers significant advantages in terms of reproducibility and reliability of experimental outcomes.

For researchers and clinicians, the value of EMD Gene Knockout Cell Lines lies in their ability to facilitate deeper insights into the genetic underpinnings of diseases, potentially leading to breakthrough therapies. As experts in the field of biological products, our company is committed to providing high-quality, customizable cell line solutions that empower scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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