Gene: ELOVL6
Official Full Name: ELOVL fatty acid elongase 6provided by HGNC
Gene Summary: Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18018 | ELOVL6 Knockout cell line (HeLa) | Human | ELOVL6 | 1:3~1:6 | Negative | Online Inquiry |
KO18019 | ELOVL6 Knockout cell line (HCT 116) | Human | ELOVL6 | 1:2~1:4 | Negative | Online Inquiry |
KO18020 | ELOVL6 Knockout cell line (HEK293) | Human | ELOVL6 | 1:3~1:6 | Negative | Online Inquiry |
KO18021 | ELOVL6 Knockout cell line (A549) | Human | ELOVL6 | 1:3~1:4 | Negative | Online Inquiry |
ELOVL6 Gene Knockout Cell Lines represent a finely engineered tool in the field of molecular biology, specifically designed for the study of lipid metabolism and associated disorders. ELOVL6 (Elongation of Very Long Chain Fatty Acids 6) is a critical enzyme involved in the elongation of long-chain fatty acids; thus, the knockout of this gene allows researchers to elucidate its biological roles and the pathways it influences.
The key function of the ELOVL6 gene knockout cell lines lies in their ability to help scientists investigate the consequences of ELOVL6 deficiency on cellular function, metabolism, and signaling pathways. Through mechanisms such as altered fatty acid composition and dysregulated lipid metabolism, these cell lines can provide insights into how ELOVL6 affects energy homeostasis, inflammation, and diseases such as obesity and non-alcoholic fatty liver disease (NAFLD).
In terms of scientific importance, these knockout models are invaluable not only for basic research but also for drug discovery and development. They serve as platforms to test potential therapies targeting lipid metabolic pathways and to assess the bioactivity of small molecules that may modulate ELOVL6 activity.
Compared to traditional cellular models, ELOVL6 Gene Knockout Cell Lines offer specificity that enables more precise investigations into specific metabolic dysfunctions and their implications for human health. The elimination of this gene results in well-characterized, reproducible cellular responses, thereby enhancing the reliability of experimental data.
For researchers and clinicians aiming to deepen their understanding of lipid biology and its implications in metabolic diseases, these cell lines present a unique opportunity. Their ability to mimic pathological conditions makes them a critical asset in developing targeted interventions.
Our company is committed to advancing scientific knowledge and research through high-quality biological products. With extensive expertise in cell line development and molecular biology, we ensure that our ELOVL6 Gene Knockout Cell Lines meet the rigorous standards required for cutting-edge research.
Please note that all services are for research use only. Not intended for any clinical use.
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