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ELMOD3 Knockout Cell Lines

Gene: ELMOD3

Official Full Name: ELMO domain containing 3provided by HGNC

Gene Summary: This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25129 ELMOD3 Knockout cell line (HeLa) Human ELMOD3 1:3~1:6 Negative Online Inquiry
KO25130 ELMOD3 Knockout cell line (HCT 116) Human ELMOD3 1:2~1:4 Negative Online Inquiry
KO25131 ELMOD3 Knockout cell line (HEK293) Human ELMOD3 1:3~1:6 Negative Online Inquiry
KO25132 ELMOD3 Knockout cell line (A549) Human ELMOD3 1:3~1:4 Negative Online Inquiry

Background

ELMOD3 Gene Knockout Cell Lines are a specialized biological product designed to facilitate in-depth research into the ELMOD3 gene's functions, which has been implicated in various cellular processes including endocytosis, cell signaling, and cytoskeletal dynamics. By employing CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete knockout of the ELMOD3 gene, allowing researchers to study the resulting phenotypic changes and gain insights into its biological roles.

The key mechanism underpinning these cell lines involves precise genome editing that disrupts the ELMOD3 gene, effectively rendering it non-functional. This disruption provides a valuable model for investigating the molecular pathways influenced by ELMOD3, offering insights into how its dysfunction may contribute to pathological conditions, including cancers and neurodegenerative diseases. Researchers can utilize these knockout models to evaluate compensatory mechanisms and potential therapeutic targets, thereby enhancing their understanding of complex biological systems.

The scientific importance of ELMOD3 Gene Knockout Cell Lines is underscored by their application in various research and clinical settings. They serve as a critical tool for drug discovery, functional genomics, and basic biological research, enabling scientists to elucidate gene function and investigate its interactions within cellular pathways. The ability to manipulate gene expression in these cell lines allows for more targeted and reliable studies compared to traditional models.

Compared to alternative gene editing approaches, ELMOD3 Gene Knockout Cell Lines provide a more refined and efficient method for conducting genetic studies. With a streamlined process that ensures reproducibility and consistency, these cell lines minimize experimental variability, thus enhancing the reliability of research outcomes.

For researchers and clinicians looking to deepen their understanding of ELMOD3-related biological processes or develop novel therapeutic strategies, our ELMOD3 Gene Knockout Cell Lines represent an invaluable resource. Our company prides itself on delivering high-quality biological products with the backing of expert knowledge and cutting-edge technology, ensuring that researchers have access to tools that drive innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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