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ELMOD1 Knockout Cell Lines

Gene: ELMOD1

Official Full Name: ELMO domain containing 1provided by HGNC

Gene Summary: Enables GTPase activator activity. Predicted to act upstream of or within cilium assembly and protein transport. Predicted to be active in Golgi apparatus; cilium; and glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18026 ELMOD1 Knockout cell line (HCT 116) Human ELMOD1 1:2~1:4 Negative Online Inquiry
KO18027 ELMOD1 Knockout cell line (HEK293) Human ELMOD1 1:3~1:6 Negative Online Inquiry

Background

ELMOD1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to express a deletion in the ELMOD1 gene, which encodes a member of the ELMOD family of proteins involved in mitochondrial dynamics and cellular signaling pathways. These knockout models serve as a crucial tool for researchers exploring the role of ELMOD1 in various biological processes, such as cellular metabolism, apoptosis, and muscle regulation.

The primary function of ELMOD1 is its involvement in the regulation of mitochondrial fusion and fission, which are essential processes for maintaining mitochondrial health and function. By disrupting the ELMOD1 gene, these cell lines facilitate the investigation of the downstream effects of impaired mitochondrial dynamics, allowing scientists to study the potential link between ELMOD1 dysfunction and various diseases, including metabolic disorders and certain neurodegenerative conditions.

The scientific importance of ELMOD1 Gene Knockout Cell Lines extends to their application in research settings aimed at understanding the mechanistic pathways of mitochondrial disorders and in identifying new therapeutic targets. In clinical research, these models can provide insights into the potential for novel interventions that might restore mitochondrial function or compensate for ELMOD1 loss.

What sets our ELMOD1 Gene Knockout Cell Lines apart from alternatives is the rigorous validation of each cell line ensuring specificity in ELMOD1 disruption without off-target effects. Furthermore, these lines are derived from widely used parent cell types, enhancing their compatibility with a broad range of assays and experimental designs.

For researchers and clinicians, the availability of highly characterized ELMOD1 Gene Knockout Cell Lines represents a valuable opportunity to advance understanding of mitochondrial biology and its implications in health and disease. Our commitment to quality and innovation in the production of these biological models underscores our expertise in delivering essential research tools that empower breakthroughs in science and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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