Gene: ELFN2
Official Full Name: extracellular leucine rich repeat and fibronectin type III domain containing 2provided by HGNC
Gene Summary: Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in synaptic membrane adhesion. Predicted to act upstream of or within chemical synaptic transmission; establishment of protein localization; and gene expression. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30753 | ELFN2 Knockout cell line (HeLa) | Human | ELFN2 | 1:3~1:6 | Negative | Online Inquiry |
KO30754 | ELFN2 Knockout cell line (HCT 116) | Human | ELFN2 | 1:2~1:4 | Negative | Online Inquiry |
KO30755 | ELFN2 Knockout cell line (A549) | Human | ELFN2 | 1:3~1:4 | Negative | Online Inquiry |
The ELFN2 Gene Knockout Cell Lines are tailored biological tools designed for the precise study of the ELFN2 gene's role in various cellular processes and disease mechanisms. These cell lines have been genetically modified to completely disrupt the expression of the ELFN2 gene, allowing researchers to investigate its function and implications in neurodevelopment, synaptic dynamics, and neurodegenerative conditions.
The key function of these knockout cell lines lies in their ability to model the absence of ELFN2, enabling the examination of downstream effects on cellular signaling pathways, neuronal morphology, and synaptic transmission. Through the knockout, researchers can explore how the loss of ELFN2 alters cell behavior, which may provide insights into its potential roles in both normal physiology and pathological states.
Scientifically, these cell lines are invaluable for academic and clinical research focusing on neurobiology, mental health disorders, and synaptic diseases. They facilitate a deeper understanding of the genetic underpinnings of conditions such as autism spectrum disorders and schizophrenia, making them crucial for developing targeted therapeutic approaches or interventions.
Compared to alternative models, such as wild-type or overexpressing models, the ELFN2 Gene Knockout Cell Lines provide a unique advantage by offering a clearer view of gene-specific functions without compensatory effects that may skew results. Additionally, these cell lines are rigorously validated and fully characterized, ensuring reliable reproducibility in experimental outcomes.
For researchers and clinicians seeking to unravel the complexities of synaptic function and its related disorders, the ELFN2 Gene Knockout Cell Lines represent an essential resource. Their ability to provide clarity on gene function can ultimately streamline pathways towards novel treatment strategies and enhance our understanding of neurogenetics.
Our company boasts years of expertise in delivering high-quality, rigorously evaluated biological products, ensuring that our offerings meet the evolving demands of the scientific community. With our ELFN2 Gene Knockout Cell Lines, we commit to supporting impactful research and fostering advancements in cellular biology and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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