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EHF Knockout Cell Lines

Gene: EHF

Official Full Name: ETS homologous factorprovided by HGNC

Gene Summary: This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28124 EHF Knockout cell line (HCT 116) Human EHF 1:2~1:4 Negative Online Inquiry
KO28125 EHF Knockout cell line (A549) Human EHF 1:3~1:4 Negative Online Inquiry

Background

EHF Gene Knockout Cell Lines are specialized research tools engineered to lack functional expression of the EHF gene, which plays a critical role in various cellular processes including transcriptional regulation and cellular differentiation. These knockout models serve as invaluable systems for studying the gene's biological functions and interactions in both basic and applied research.

The key mechanism by which EHF Gene Knockout Cell Lines operate involves the targeted disruption of the EHF gene locus, typically achieved using advanced genome-editing techniques such as CRISPR/Cas9. This precise alteration enables researchers to investigate the physiological implications of EHF deficiency, ranging from gene expression changes to alterations in metabolic pathways. By analyzing these knockout lines, scientists can glean insights into disease mechanisms, particularly those associated with cancer and developmental disorders, ultimately leading to the identification of novel therapeutic targets.

The scientific importance of EHF Gene Knockout Cell Lines is underscored by their diverse applications in molecular biology, pharmacology, and biotechnology. In clinical settings, they can facilitate drug discovery processes by allowing for the assessment of drug efficacy and toxicity in a controlled environment. Furthermore, these cell lines enable the exploration of gene function in response to external stimuli, thereby contributing to a deeper understanding of cellular responses in health and disease.

One of the distinct advantages of our EHF Gene Knockout Cell Lines is their validated knockout status, which assures researchers of the reliability and reproducibility of their results. Compared to alternative models, our product is meticulously characterized and includes comprehensive validation data, so users can feel confident about their experimental outcomes. Additionally, the ease of use and compatibility with commonly employed laboratory techniques make these cell lines an ideal choice for both seasoned researchers and those newly entering the field.

As a company deeply committed to advancing biological research, we at [Company Name] pride ourselves on our extensive expertise in gene editing technologies and cell line development. Our EHF Gene Knockout Cell Lines are not just products; they represent a partnership in scientific discovery, empowering researchers and clinicians to push the boundaries of knowledge and innovation in biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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