Gene: ECEL1
Official Full Name: endothelin converting enzyme like 1provided by HGNC
Gene Summary: This gene encodes a member of the M13 family of endopeptidases. Members of this family are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Mutations in this gene are associated with autosomal recessive distal arthrogryposis, type 5D. This gene has multiple pseudogenes on chromosome 2. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05677 | ECEL1 Knockout cell line (HeLa) | Human | ECEL1 | 1:3~1:6 | Negative | Online Inquiry |
KO05678 | ECEL1 Knockout cell line (HEK293) | Human | ECEL1 | 1:3~1:6 | Negative | Online Inquiry |
ECEL1 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology that allows researchers to study gene function and disease mechanisms by specifically disrupting the ECEL1 gene expression. This product harnesses advanced CRISPR-Cas9 genetic engineering techniques to create precise knockout models, enabling scientists to elucidate the role of ECEL1 in various physiological and pathological processes. The knockout mechanism effectively silences the gene, leading to an absence or significant reduction of ECEL1 protein, providing a unique platform for in-depth functional assays.
The key functions of these cell lines include investigating the downstream effects of ECEL1 absence on cellular behavior, signaling pathways, and gene expression profiles. This is particularly essential in the context of studies related to neurodegenerative diseases, developmental biology, and regenerative medicine, where ECEL1's involvement has garnered increasing interest. With the ability to perform comparative studies against wild-type cell lines, researchers can gain critical insights into ECEL1's biological significance.
In both research and clinical applications, ECEL1 Gene Knockout Cell Lines facilitate high-throughput screening and provide a reliable model for drug discovery and development, particularly for therapeutics targeting related diseases. The specificity and reliability of these cell lines not only streamline one’s research but also enhance reproducibility, which is often a challenge in biomedical studies.
The advantages of the ECEL1 Gene Knockout Cell Lines over conventional models include their precision, customizability, and the ability to capture a more relevant biological response to the loss of ECEL1 function. Unlike traditional methods, these cell lines eliminate off-target effects typically associated with older genetic manipulation techniques, ensuring that observed phenotypes are truly a result of ECEL1 disruption.
For researchers and clinicians invested in advancing our understanding of gene function and its implication in health and disease, these cell lines provide a distinctly valuable resource. Their adoption can accelerate the pace of discovery and therapeutic innovation. Our company prides itself on leading in genetic engineering technologies and providing high-quality biological products that enhance the research landscape. By choosing ECEL1 Gene Knockout Cell Lines, users will be empowered with precise tools designed to drive significant scientific breakthroughs.
Please note that all services are for research use only. Not intended for any clinical use.
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