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EBF3 Knockout Cell Lines

Gene: EBF3

Official Full Name: EBF transcription factor 3provided by HGNC

Gene Summary: This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21214 EBF3 Knockout cell line (HEK293) Human EBF3 1:3~1:6 Negative Online Inquiry

Background

EBF3 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the EBF3 gene and its associated biological pathways. This product involves the precise alteration of the EBF3 gene using advanced CRISPR-Cas9 technology, resulting in a complete disruption of its function. EBF3, or Early B Cell Factor 3, plays a vital role in the regulation of immune responses and neurodevelopment, making these knockout cell lines essential for investigating its contributions to various physiological and pathological processes.

The key function of the EBF3 Gene Knockout Cell Lines lies in their ability to provide researchers with a controlled environment to analyze the effects of EBF3 deficiency. By eliminating this gene, these cell lines enable the study of resultant changes in gene expression profiles, signaling pathways, and cellular behaviors. The alterations observed can shed light on EBF3's role in B cell differentiation, neurogenesis, and other developmental processes, thereby offering insights into diseases such as immunodeficiencies and neurodevelopmental disorders.

Scientifically, these knockout cell lines are invaluable in both fundamental and applied research settings. They serve as critical tools for drug discovery, genetic screening, and the development of targeted therapies. By allowing for the elucidation of the functions and mechanisms of EBF3, researchers can better understand its implications in health and disease, paving the way for innovative treatment strategies.

What sets EBF3 Gene Knockout Cell Lines apart from alternative models is their reliability and reproducibility, coupled with our comprehensive validation process. Each cell line is extensively characterized, ensuring consistent performance across experiments. Moreover, these models are ready-to-use, significantly reducing preparation time and enhancing experimental efficiency.

For researchers and clinicians, the EBF3 Gene Knockout Cell Lines represent a significant advancement in the toolkit available for genetic and translational research. They exemplify our commitment to providing high-quality, cutting-edge biological products that empower scientific innovation. Our company leverages extensive expertise in genetics and cell biology to deliver products that meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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