Gene: EBF1
Official Full Name: EBF transcription factor 1provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07069 | EBF1 Knockout cell line (HeLa) | Human | EBF1 | 1:3~1:6 | Negative | Online Inquiry |
KO07070 | EBF1 Knockout cell line (A549) | Human | EBF1 | 1:3~1:4 | Negative | Online Inquiry |
EBF1 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the Early B Cell Factor 1 (EBF1) gene, a crucial transcription factor involved in B cell development and function. These cell lines are generated through precise CRISPR-Cas9 gene-editing technology, resulting in the complete disruption of the EBF1 gene, allowing researchers to investigate the resultant phenotypic changes in B cell lineage commitment, cell proliferation, and differentiation.
The primary function of these knockout cell lines is to provide a robust platform for dissecting the molecular mechanisms underlying B cell development and related immunological processes. The absence of EBF1 in these cells mimics the pathophysiological conditions seen in various immune disorders and lymphoproliferative diseases, making it an invaluable tool for basic and translational research. Researchers can utilize these models to conduct gene expression analyses, signaling pathway studies, and drug screening, thereby contributing significantly to our understanding of humoral immunity and potential therapeutic interventions.
What sets EBF1 Gene Knockout Cell Lines apart from conventional cell models is their specificity and reliability. They eliminate the background noise associated with non-specific gene expression, providing a clearer insight into the EBF1 gene's functions. Moreover, these lines are rigorously characterized and validated for consistency in performance across multiple experiments, ensuring reproducibility and reliability of results.
For researchers and clinicians focused on immunology, hematology, or oncology, these knockout cell lines offer a vital resource for discovering new insights into disease mechanisms, potential biomarker identification, and therapeutic targets. The availability of such specialized tools accelerates the pace of discovery, ultimately allowing for faster advancements in clinical applications.
As a leader in the development of innovative biological research tools, our company is committed to delivering high-quality products backed by extensive expertise in genetics and cell biology. The EBF1 Gene Knockout Cell Lines exemplify our dedication to empowering the scientific community with resources that propel their research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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