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EBAG9 Knockout Cell Lines

Gene: EBAG9

Official Full Name: estrogen receptor binding site associated antigen 9provided by HGNC

Gene Summary: This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33510 EBAG9 Knockout cell line (HeLa) Human EBAG9 1:3~1:6 Negative Online Inquiry
KO33511 EBAG9 Knockout cell line (HCT 116) Human EBAG9 1:2~1:4 Negative Online Inquiry
KO33512 EBAG9 Knockout cell line (HEK293) Human EBAG9 1:3~1:6 Negative Online Inquiry
KO33513 EBAG9 Knockout cell line (A549) Human EBAG9 1:3~1:4 Negative Online Inquiry

Background

EBAG9 Gene Knockout Cell Lines represent a sophisticated tool for the investigation of the EBAG9 gene, known for its role in various cellular processes including tumor progression and immune responses. These cell lines are generated through advanced gene editing techniques such as CRISPR-Cas9, ensuring efficient and precise knockout of the EBAG9 gene, which allows researchers to dissect its functional contributions in a controlled environment.

The primary function of EBAG9 is implicated in modulating anti-apoptotic signaling pathways, thus enabling the survival of cancer cells under stress conditions. By using these knockout cell lines, scientists can elucidate the role of EBAG9 in oncogenesis, study its influence on cell survival, migration, and invasion, and explore how it interacts with other molecular pathways. This deep understanding is essential for developing targeted therapies, especially in cancers where EBAG9 expression is dysregulated.

The scientific importance of EBAG9 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In research settings, these lines facilitate high-throughput screening for potential drug compounds that could disrupt EBAG9 activity, while in clinical scenarios, they provide insights that can guide personalized medicine approaches. The availability of knockout models allows for more nuanced studies of genetic factors in disease, enhancing our ability to design effective interventions.

When compared to traditional cell lines, EBAG9 Gene Knockout Cell Lines offer superior specificity and reliability. They eliminate confounding variables associated with partial gene expression, allowing for clearer interpretation of results. This quality makes them particularly appealing to researchers seeking to generate reproducible outcomes in their studies.

Investing in EBAG9 Gene Knockout Cell Lines signifies a commitment to advancing cancer research and therapeutic development. The use of these specialized tools speaks to a broader goal of unraveling the complexities of tumor biology, ultimately contributing to improved patient outcomes. Our company, with its extensive experience in developing cutting-edge biological products, stands ready to support researchers and clinicians with high-quality solutions tailored to their specific needs.

Please note that all services are for research use only. Not intended for any clinical use.

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