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DZIP3 Knockout Cell Lines

Gene: DZIP3

Official Full Name: DAZ interacting zinc finger protein 3provided by HGNC

Gene Summary: Enables several functions, including phosphatase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-protein transferase activity. Involved in protein polyubiquitination. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32950 DZIP3 Knockout cell line (HeLa) Human DZIP3 1:3~1:6 Negative Online Inquiry
KO32951 DZIP3 Knockout cell line (HCT 116) Human DZIP3 1:2~1:4 Negative Online Inquiry
KO32952 DZIP3 Knockout cell line (HEK293) Human DZIP3 1:3~1:6 Negative Online Inquiry
KO32953 DZIP3 Knockout cell line (A549) Human DZIP3 1:3~1:4 Negative Online Inquiry

Background

DZIP3 Gene Knockout Cell Lines are engineered cellular models that have been specifically designed to facilitate the functional study of the DZIP3 gene (encoding for the Depletion of Zinc Finger Protein 3). This product utilizes advanced CRISPR-Cas9 technology to create precise deletions within the gene, effectively creating a knockout phenotype. The utility of these cell lines lies in their ability to provide insights into the biological roles of DZIP3, particularly in processes such as RNA metabolism and cellular response to stressors, enabling researchers to explore novel pathways influencing gene expression and protein synthesis.

The primary mechanism of these cell lines involves the disruption of the DZIP3 gene, which subsequently alters downstream signaling pathways, cellular responses, and gene networks. By studying these knockout cell lines, researchers can investigate the implications of DZIP3 in various physiology-related processes, including cancer development and progression, as well as its potential role in other biomedical fields such as neurobiology and developmental biology.

Scientifically, DZIP3 Gene Knockout Cell Lines hold significant value in both research and clinical contexts. They serve as a powerful tool for elucidating the gene's functions, validating potential therapeutic targets, and screening for medicinal compounds in drug discovery efforts. Furthermore, these cell lines provide a foundation for translational applications, wherein findings can be translated into clinical practice, particularly in the realm of personalized medicine.

Compared to alternative models, such as transient knockdowns or less specific gene-editing approaches, these DZIP3 knockout cell lines offer enhanced stability and reproducibility for long-term studies. Their robust genetic modification ensures that researchers can obtain more accurate and reliable data, bolstering the scientific rigor of their experiments.

For researchers and clinicians focused on unraveling the complexities of gene function and regulation, the DZIP3 Gene Knockout Cell Lines are invaluable assets that streamline experimental workflows, accelerate discoveries, and foster innovation in therapeutic exploration. Our company, a leader in providing high-quality biological tools, is dedicated to equipping the scientific community with reliable products that advance research and clinical endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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