Gene: DYRK4
Official Full Name: dual specificity tyrosine phosphorylation regulated kinase 4provided by HGNC
Gene Summary: This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02928 | DYRK4 Knockout cell line (HeLa) | Human | DYRK4 | 1:3~1:6 | Negative | Online Inquiry |
KO02929 | DYRK4 Knockout cell line (HCT 116) | Human | DYRK4 | 1:2~1:4 | Negative | Online Inquiry |
KO02930 | DYRK4 Knockout cell line (HEK293) | Human | DYRK4 | 1:3~1:6 | Negative | Online Inquiry |
KO02931 | DYRK4 Knockout cell line (A549) | Human | DYRK4 | 1:3~1:4 | Negative | Online Inquiry |
DYRK4 Gene Knockout Cell Lines are specially engineered cellular models that lack the DYRK4 gene, a crucial component in various biological processes including cell signaling and developmental regulation. These cell lines provide researchers with a powerful tool to investigate the functions of the DYRK4 gene, its role in disease pathogenesis, and the molecular mechanisms that underlie various physiological processes.
The key function of the DYRK4 gene knockout cell lines lies in facilitating the study of gene function through the elimination of specific genetic interactions. By disrupting DYRK4 expression, researchers can observe alterations in cell behavior, signaling pathways, and gene expression profiles. These changes provide insight into DYRK4's influence on cellular differentiation, proliferation, and response to external stimuli, thereby contributing to a deeper understanding of its involvement in various diseases, including cancer and neurological disorders.
Scientifically, these knockout cell lines are invaluable in both research and clinical settings. They enable the development and validation of therapeutic strategies targeting DYRK4 and assist in drug discovery by providing a relevant model system for screening potential small molecules that can modulate DYRK4's activity. Additionally, these cell lines can be instrumental in uncovering biomarkers for diseases associated with aberrant DYRK4 function, thus advancing personalized medicine approaches.
What sets DYRK4 Gene Knockout Cell Lines apart from traditional models is their specificity and adaptability for high-throughput screening applications. Unlike conventional cell lines, these models offer a targeted approach to studying gene function with increased accuracy, minimizing off-target effects. This specificity enhances experimental reproducibility and reduces the time and resources spent on project development.
Researchers, clinicians, and pharmaceutical scientists will find the value of these knockout cell lines lies not only in their ability to simplify complex biology but also in their role in advancing therapeutic innovations. By using these models, scientists can contribute to the growing body of knowledge surrounding the DYRK family of kinases and their potential as drug targets.
With years of expertise in developing cutting-edge biological products, our company is committed to providing high-quality, reliable tools that empower researchers and clinicians to make significant advancements in understanding disease mechanisms and therapeutic strategies. Our DYRK4 Gene Knockout Cell Lines exemplify this commitment to excellence in biotechnology.
Please note that all services are for research use only. Not intended for any clinical use.
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