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DUX5 Knockout Cell Lines

Gene: DUX5

Official Full Name: double homeobox 5provided by HGNC

Gene Summary: The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28033 DUX5 Knockout cell line (HeLa) Human DUX5 1:3~1:6 Negative Online Inquiry
KO28034 DUX5 Knockout cell line (HCT 116) Human DUX5 1:2~1:4 Negative Online Inquiry
KO28035 DUX5 Knockout cell line (HEK293) Human DUX5 1:3~1:6 Negative Online Inquiry
KO28036 DUX5 Knockout cell line (A549) Human DUX5 1:3~1:4 Negative Online Inquiry

Background

DUX5 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the DUX5 gene, a critical player in early developmental gene regulation and muscle differentiation. By employing CRISPR-Cas9 technology, these cell lines have been precisely modified to disrupt the DUX5 gene's function, allowing researchers to investigate its role in various biological processes and disease mechanisms.

The primary function of these knockout cell lines lies in their ability to mimic disease conditions, making them invaluable for elucidating the pathways in which DUX5 is involved. By studying these modified cells, scientists can explore how the loss of DUX5 contributes to disorders such as certain muscular dystrophies or influences cellular responses to stress and nutrient availability. The systematic analysis of these knockout lines allows for a deeper understanding of gene regulation, cell signaling, and the molecular underpinnings of related pathologies.

From a scientific perspective, DUX5 Gene Knockout Cell Lines serve as essential tools in both basic and applied research settings. They can be utilized in drug discovery processes, enabling the screening of therapeutic agents that might mitigate the effects of DUX5 dysregulation. Moreover, they offer potential insights for genetic and regenerative medicine, contributing to advancements in targeted therapies.

What sets our DUX5 knockout cell lines apart from competitors is their unparalleled reliability and robustness, validated through extensive characterization testing. Each line is produced under stringent conditions, ensuring consistent performance and reproducibility across experiments. Additionally, these cell lines are customizable, allowing researchers to select various backgrounds or additional genetic modifications as needed.

Our DUX5 Gene Knockout Cell Lines present a significant advantage to researchers and clinicians aiming to unravel complex genetic pathways and develop innovative solutions for muscle-related diseases. By leveraging years of expertise in genetics and cell biology, our company is committed to providing high-quality, scientifically accurate biological products that empower the scientific community and drive groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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