Gene: DUX1
Official Full Name: double homeobox 1provided by HGNC
Gene Summary: The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX1, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28025 | DUX1 Knockout cell line (HeLa) | Human | DUX1 | 1:3~1:6 | Negative | Online Inquiry |
KO28026 | DUX1 Knockout cell line (HCT 116) | Human | DUX1 | 1:2~1:4 | Negative | Online Inquiry |
KO28027 | DUX1 Knockout cell line (HEK293) | Human | DUX1 | 1:3~1:6 | Negative | Online Inquiry |
KO28028 | DUX1 Knockout cell line (A549) | Human | DUX1 | 1:3~1:4 | Negative | Online Inquiry |
DUX1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of DUX1 gene function and its implications in various biological processes and diseases. DUX1, or Double Homeobox 1, plays critical roles in the early development and regulation of gene expression, thereby influencing cellular differentiation and proliferation. The knockout of this gene via targeted genome editing techniques, such as CRISPR-Cas9, results in cell lines that lack functional DUX1 products, providing a powerful tool for elucidating its biological roles.
These cell lines enable researchers to dissect the mechanisms underlying DUX1-related pathways, offering insight into its involvement in disorders such as facioscapulohumeral muscular dystrophy (FSHD) and other developmental abnormalities. By investigating the degenerative and regulatory functions of DUX1, these models can significantly advance our understanding of genetic regulation, muscle pathology, and potential therapeutic strategies.
Compared to traditional methods of gene disruption, DUX1 Gene Knockout Cell Lines offer several advantages. Their precise genome editing allows for consistent genetic modifications, leading to reproducible experiments. This feature ensures that researchers can obtain reliable data while saving time and reducing variability often encountered with less targeted approaches. Additionally, these cell lines come with comprehensive documentation and validation data, providing users confidence in their results.
For researchers and clinicians focused on genetic research, regenerative medicine, or drug development, DUX1 Gene Knockout Cell Lines represent an invaluable resource. They not only streamline experimental design but also enhance the rigor and depth of insights into the biological impact of DUX1 deficiencies.
Our company’s expertise in cutting-edge gene editing technologies and commitment to quality ensures that products like the DUX1 Gene Knockout Cell Lines meet the highest scientific standards. We are dedicated to empowering the scientific community with innovative tools that push the boundaries of research and therapeutic exploration.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.