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DUS3L Knockout Cell Lines

Gene: DUS3L

Official Full Name: dihydrouridine synthase 3 likeprovided by HGNC

Gene Summary: Enables mRNA dihydrouridine synthase activity and tRNA-dihydrouridine47 synthase activity. Involved in regulation of translation and tRNA dihydrouridine synthesis. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00376 DUS3L gRNA1-gRNA2 KO plasmid DUS3L $850
GP00422 DUS3L gRNA7-gRNA2 KO plasmid DUS3L $850
KO00711 DUS3L Knockout cell line(786-O) Human DUS3L 1:2-1:4 Negative Online Inquiry
KO00727 DUS3L Knockout cell line (Hep G2) Human DUS3L 1:2~1:4 Negative Online Inquiry
KO00738 DUS3L Knockout cell line (HeLa) Human DUS3L 1:3~1:6 Negative Online Inquiry
KO18141 DUS3L Knockout cell line (HCT 116) Human DUS3L 1:2~1:4 Negative Online Inquiry
KO18142 DUS3L Knockout cell line (HEK293) Human DUS3L 1:3~1:6 Negative Online Inquiry
KO18143 DUS3L Knockout cell line (A549) Human DUS3L 1:3~1:4 Negative Online Inquiry

Background

DUS3L Gene Knockout Cell Lines are engineered cell models designed to facilitate the investigation of gene function through targeted disruption of the DUS3L gene. These knockout cell lines serve as vital tools for researchers aiming to elucidate the molecular pathways regulated by DUS3L, a gene implicated in various biological processes such as RNA metabolism and stress responses. The mechanism behind the DUS3L knockout involves the utilization of CRISPR/Cas9 technology, which allows for precise genomic editing. This method ensures that the DUS3L gene is effectively rendered non-functional, thereby enabling the exploration of its effects on cellular behavior.

The scientific importance of DUS3L Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. These cell lines provide a robust platform for studying gene interactions, potential pathways for disease progression, and responses to therapeutic interventions. Additionally, they can be employed in drug discovery, allowing for the screening of compounds that may influence cellular processes modulated by DUS3L.

What sets our DUS3L Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability, as each line undergoes thorough validation to ensure the complete knockout of the target gene without significant off-target effects. Furthermore, these cell lines are developed in well-characterized backgrounds, providing consistency across experiments.

For researchers and clinicians, DUS3L Gene Knockout Cell Lines offer unparalleled value through their ability to accelerate discoveries in gene function and disease mechanisms, ultimately paving the way for innovative therapeutic strategies. Our commitment to precision in genetic engineering, combined with our extensive expertise in developing biological models, ensures that customers receive high-quality products that meet rigorous scientific standards for their research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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