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DTX3 Knockout Cell Lines

Gene: DTX3

Official Full Name: deltex E3 ubiquitin ligase 3provided by HGNC

Gene Summary: DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11420 DTX3 Knockout cell line (HeLa) Human DTX3 1:3~1:6 Negative Online Inquiry
KO11421 DTX3 Knockout cell line (HEK293) Human DTX3 1:3~1:6 Negative Online Inquiry
KO11422 DTX3 Knockout cell line (A549) Human DTX3 1:3~1:4 Negative Online Inquiry

Background

DTX3 Gene Knockout Cell Lines represent a groundbreaking advancement in the field of genetic research and cellular biology. These cell lines are specifically engineered to harbor a complete knockout of the DTX3 gene, which plays a pivotal role in the ubiquitin-proteasome pathway and influences various cellular processes, including cell cycle regulation and apoptosis. By providing a model that lacks DTX3, researchers can dissect the gene's function in biological pathways, elucidate its involvement in disease mechanisms, and explore its potential as a therapeutic target.

The DTX3 knockout mechanism harnesses advanced CRISPR-Cas9 technology, yielding precise modifications that ensure complete ablation of gene function. This allows for investigation of DTX3's downstream effects on cellular signaling and gene expression, facilitating a deeper understanding of its contributions to diseases such as cancer, immune disorders, and neurodegenerative conditions.

The scientific importance of DTX3 Gene Knockout Cell Lines is underscored by their applications in various research domains. In drug discovery, these cell lines serve as critical tools for screening potential therapeutics that modulate the signaling pathways associated with DTX3. Furthermore, they are instrumental in elucidating the molecular underpinnings of DTX3-related pathologies, providing insights necessary for developing targeted therapies.

What sets our DTX3 Gene Knockout Cell Lines apart from alternative models is their validated performance and reproducibility, paired with the comprehensive support offered by our team of experts. Unlike less specialized knockout lines, our product comes with a detailed characterization report, ensuring confidence in experimental results. Additionally, we provide extensive technical assistance, making this an invaluable resource for both seasoned researchers and teams embarking on this novel area of study.

In conclusion, the DTX3 Gene Knockout Cell Lines are an essential addition to any biological research laboratory focused on gene function and the exploration of disease mechanisms. Backed by our company's expertise in genetic engineering and cell line development, we are committed to providing superior products that empower researchers and clinicians to push the boundaries of scientific knowledge and therapeutic innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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