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DRG1 Knockout Cell Lines

Gene: DRG1

Official Full Name: developmentally regulated GTP binding protein 1provided by HGNC

Gene Summary: Enables several functions, including GTPase activity; identical protein binding activity; and potassium ion binding activity. Involved in positive regulation of microtubule polymerization and regulation of mitotic spindle assembly. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06588 DRG1 Knockout cell line (HeLa) Human DRG1 1:3~1:6 Negative Online Inquiry
KO06589 DRG1 Knockout cell line (HCT 116) Human DRG1 1:2~1:4 Negative Online Inquiry
KO06590 DRG1 Knockout cell line (HEK293) Human DRG1 1:3~1:6 Negative Online Inquiry
KO06591 DRG1 Knockout cell line (A549) Human DRG1 1:3~1:4 Negative Online Inquiry

Background

DRG1 Gene Knockout Cell Lines are genetically engineered cellular models that specifically lack the expression of the DRG1 gene, which is implicated in various cellular processes, including cell growth, proliferation, and response to stress. These unique cell lines serve as essential tools for researchers seeking to elucidate the functional role of DRG1 in both normal physiology and pathological conditions.

The primary function of these knockout cell lines is to permit a deeper investigation into the biological pathways influenced by DRG1. By comparing the behavior of knockout lines to their wild-type counterparts, researchers can discern how the absence of this gene affects cellular mechanisms, including apoptosis, differentiation, and tumorigenesis. The well-characterized methods of gene editing utilized to create these lines, such as CRISPR-Cas9, ensure precision and reproducibility, allowing for consistent experimental outcomes.

In the realm of scientific research, these cell lines are invaluable for studies focused on cancer biology, neurobiology, and responses to therapeutic agents. They provide a platform for screening drugs that may interact with pathways associated with DRG1, facilitating the development of targeted therapies and enhancing our understanding of various diseases.

Compared to alternative methods, such as transient transfection or unspecific gene silencing techniques, DRG1 Gene Knockout Cell Lines offer a stable, permanent alteration that yields more reliable data over extended experimental periods. This stability makes them particularly advantageous for long-term experiments and high-throughput screening applications.

For researchers, clinicians, and pharmaceutical companies, the value of DRG1 Gene Knockout Cell Lines lies in their ability to advance knowledge and innovation in the field of molecular biology and therapeutic development. By acquiring these specialized cell lines, users can leverage our deep expertise in genetic engineering and cell line development, ensuring that they have access to high-quality and well-characterized biological tools that meet rigorous scientific standards.

Please note that all services are for research use only. Not intended for any clinical use.

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