Gene: DRC3
Official Full Name: dynein regulatory complex subunit 3provided by HGNC
Gene Summary: Located in axoneme. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25498 | DRC3 Knockout cell line (HeLa) | Human | DRC3 | 1:3~1:6 | Negative | Online Inquiry |
KO25499 | DRC3 Knockout cell line (HCT 116) | Human | DRC3 | 1:2~1:4 | Negative | Online Inquiry |
KO25500 | DRC3 Knockout cell line (HEK293) | Human | DRC3 | 1:3~1:6 | Negative | Online Inquiry |
KO25501 | DRC3 Knockout cell line (A549) | Human | DRC3 | 1:3~1:4 | Negative | Online Inquiry |
DRC3 Gene Knockout Cell Lines are genetically engineered cellular models designed to lack the expression of the DRC3 gene, a component known to play an essential role in cellular processes such as cell division and ciliary function. These knockout cell lines serve as valuable tools for researchers investigating the genetic and molecular mechanisms underlying various diseases, particularly those influenced by ciliary dysfunction, including certain respiratory and neurological conditions.
The primary function of DRC3 Gene Knockout Cell Lines is to provide insights into the physiological roles and downstream effects of DRC3 absence on cell behavior and signaling pathways. By removing the DRC3 gene, these cell lines allow for the observation of alterations in cellular metabolism, proliferation, and response to environmental stimuli compared to wild-type cells. This mechanistic understanding is critical in elucidating the gene's contribution to pathophysiological states and can lead to the identification of potential therapeutic targets.
In research and clinical settings, DRC3 Gene Knockout Cell Lines are invaluable for drug screening and biomarker discovery, enabling the assessment of novel therapeutics’ effects on ciliary-related disorders. They also facilitate the development of gene therapies and other treatment modalities by providing a relevant platform for the validation of genetic interventions.
Compared to traditional cell lines, DRC3 Gene Knockout Cell Lines offer a unique advantage due to their specificity; researchers gain a high degree of confidence that observed phenotypic changes are directly attributable to the absence of DRC3. Furthermore, alongside their reliable performance, these cell lines come with thorough validation and characterization, ensuring reproducibility and robustness in experimental design.
Choosing DRC3 Gene Knockout Cell Lines empowers researchers and clinicians with a cutting-edge resource for advancing our understanding of disease mechanisms and developing tailored interventions. Backed by our team of experts with extensive experience in genetic engineering and cellular biology, our commitment to quality and innovation positions our product at the forefront of biological research tools, ensuring that you can rely on us for your scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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