Gene: DOP1B
Official Full Name: DOP1 leucine zipper like protein Bprovided by HGNC
Gene Summary: Involved in cognition and embryonic pattern specification. Located in early endosome membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32406 | DOP1B Knockout cell line (HeLa) | Human | DOP1B | 1:3~1:6 | Negative | Online Inquiry |
KO32407 | DOP1B Knockout cell line (HCT 116) | Human | DOP1B | 1:2~1:4 | Negative | Online Inquiry |
KO32408 | DOP1B Knockout cell line (HEK293) | Human | DOP1B | 1:3~1:6 | Negative | Online Inquiry |
KO32409 | DOP1B Knockout cell line (A549) | Human | DOP1B | 1:3~1:4 | Negative | Online Inquiry |
DOP1B Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the DOP1B gene, which is involved in various physiological processes, including neurotransmission and phototransduction. By utilizing CRISPR/Cas9 technology, these cell lines exhibit a complete knockout of the DOP1B gene, providing researchers with a powerful tool to investigate the gene’s functional role and its implications in health and disease.
The key function of DOP1B Gene Knockout Cell Lines lies in their ability to mimic a loss-of-function context for the DOP1B gene, allowing for the analysis of downstream signaling pathways, cellular responses, and potential compensatory mechanisms in the absence of DOP1B activity. Researchers can utilize these models to perform a range of assays, including drug screening, gene expression analysis, and cellular phenotypic studies, enabling deeper insights into the biological mechanisms that underlie disorders related to the DOP1B gene.
The scientific importance of DOP1B Gene Knockout Cell Lines is underscored by their applications in both basic research and therapeutic development. They provide invaluable data that could lead to novel therapeutic strategies for conditions such as schizophrenia, depression, and retinal disorders. By facilitating the exploration of gene function and interaction networks, these cell lines can ultimately contribute to advancing personalized medicine approaches.
Compared to conventional knockdown methods, DOP1B Gene Knockout Cell Lines offer several advantages, including stable expression of the knockout phenotype and the ability to evaluate gene function over extended time frames without the risk of off-target effects common with RNA interference techniques. This robustness makes them a more reliable choice for long-term studies.
For researchers, clinicians, and institutions aiming to deepen their understanding of genetic function and its implications in disease, DOP1B Gene Knockout Cell Lines provide exceptional value. The precision in gene editing, coupled with the detailed functional insights these models offer, positions them as essential tools in the pursuit of biomedical innovation.
Our company has a proven track record in developing cutting-edge genetic models, and we are committed to empowering scientific exploration with high-quality biological products designed to meet the evolving needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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