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DNAL4 Knockout Cell Lines

Gene: DNAL4

Official Full Name: dynein axonemal light chain 4provided by HGNC

Gene Summary: This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32265 DNAL4 Knockout cell line (HeLa) Human DNAL4 1:3~1:6 Negative Online Inquiry
KO32266 DNAL4 Knockout cell line (HCT 116) Human DNAL4 1:2~1:4 Negative Online Inquiry
KO32267 DNAL4 Knockout cell line (HEK293) Human DNAL4 1:3~1:6 Negative Online Inquiry
KO32268 DNAL4 Knockout cell line (A549) Human DNAL4 1:3~1:4 Negative Online Inquiry

Background

DNAL4 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to help researchers study the biological functions and pathways associated with the DNAL4 gene. By utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines provide a valuable resource for investigating gene expression, protein function, and cellular responses in various contexts. The mechanism behind the knockout is based on targeted disruption of the DNAL4 gene, allowing researchers to observe the resulting phenotypic changes and gain insights into the gene's role in cellular and molecular biology.

The scientific importance of DNAL4 knockout cell lines lies in their applications across multiple research disciplines, including cancer biology, immunology, and regenerative medicine. By eliminating the expression of DNAL4, researchers are equipped to identify the implications of its absence on cellular mechanisms, signaling pathways, and therapeutic responses. Such insights are instrumental for developing targeted therapies and understanding disease etiology.

One significant advantage of our DNAL4 Gene Knockout Cell Lines over alternatives is the precision and reliability of our CRISPR/Cas9 methodology, which results in clean and specific gene disruptions without off-target effects. The cell lines are extensively validated for consistent performance, ensuring reproducibility in various experimental settings.

Moreover, these knockout cell lines are provided with comprehensive support, including detailed Usage Protocols and troubleshooting guidance. This not only streamlines experimental processes but also facilitates the integration of the product into ongoing research frameworks.

In summary, DNAL4 Gene Knockout Cell Lines serve as an indispensable tool for researchers and clinicians aiming to unravel the complexities of gene function and its implications in health and disease. Our company prides itself on its commitment to innovation and quality, ensuring that our products enhance scientific discovery and contribute to advancements in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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