Gene: DNAJC4
Official Full Name: DnaJ heat shock protein family (Hsp40) member C4provided by HGNC
Gene Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding and response to unfolded protein. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37157 | DNAJC4 Knockout cell line (HeLa) | Human | DNAJC4 | 1:3~1:6 | Negative | Online Inquiry |
KO37158 | DNAJC4 Knockout cell line (HCT 116) | Human | DNAJC4 | 1:2~1:4 | Negative | Online Inquiry |
KO37159 | DNAJC4 Knockout cell line (HEK293) | Human | DNAJC4 | 1:3~1:6 | Negative | Online Inquiry |
KO37160 | DNAJC4 Knockout cell line (A549) | Human | DNAJC4 | 1:3~1:4 | Negative | Online Inquiry |
DNAJC4 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate research into the functions and implications of the DNAJC4 gene. The DNAJC4 gene encodes a member of the DnaJ heat shock protein family, known for its critical role in protein folding and cellular stress response mechanisms. By utilizing CRISPR/Cas9 technology to create knockout variants of these cell lines, researchers can investigate the downstream effects of DNAJC4 deficiency, providing insights into the gene’s involvement in various biological processes and disease states.
The primary function of DNAJC4 gene knockout cell lines is to enable scientists to assess changes in cellular behavior following the loss of DNAJC4 activity. By analyzing alterations in protein expression, stress response pathways, and cellular signaling mechanisms, researchers can delineate the specific roles that DNAJC4 plays in pathophysiological conditions such as neurodegenerative diseases and cancer. This line of inquiry is particularly important, given the growing interest in targeting molecular chaperones and co-chaperones in therapeutic strategies.
From a scientific perspective, these cell lines represent a robust tool for both fundamental research and clinical applications, allowing for high-throughput screening assays and drug development studies. Detailed exploration of the DNJAC4 gene's functions enhances understanding of cellular homeostasis and could yield potential targets for intervention in a variety of diseases.
In comparison to conventional knockout models, our DNAJC4 gene knockout cell lines offer enhanced specificity and efficiency, minimizing off-target effects and maximizing experimental reproducibility. This level of precision ensures that researchers can confidently interpret data and make informed decisions based on their findings, which is crucial for experimental rigor.
Ultimately, DNAJC4 Gene Knockout Cell Lines present an invaluable resource for researchers and clinicians aiming to deepen their understanding of protein homeostasis and its implications in human health and disease. Our company prides itself on being at the forefront of innovative biological products, leveraging cutting-edge technologies to support the scientific community in unveiling the complexities of gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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