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DNAJC27 Knockout Cell Lines

Gene: DNAJC27

Official Full Name: DnaJ heat shock protein family (Hsp40) member C27provided by HGNC

Gene Summary: Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in cytoplasmic vesicle and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22755 DNAJC27 Knockout cell line (HeLa) Human DNAJC27 1:3~1:6 Negative Online Inquiry
KO22756 DNAJC27 Knockout cell line (HCT 116) Human DNAJC27 1:2~1:4 Negative Online Inquiry
KO22757 DNAJC27 Knockout cell line (HEK293) Human DNAJC27 1:3~1:6 Negative Online Inquiry
KO22758 DNAJC27 Knockout cell line (A549) Human DNAJC27 1:3~1:4 Negative Online Inquiry

Background

DNAJC27 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the DNAJC27 gene, a member of the DnaJ heat shock protein family involved in various cellular processes, including protein folding and stress responses. These knockout cell lines serve as invaluable tools in biological research, allowing for the dissection of the gene's functions and its implications in diseases such as neurodegeneration and cancer.

The primary function of DNAJC27 is to assist in the proper folding of nascent proteins and manage protein quality control within the endoplasmic reticulum. By utilizing these knockout cell lines, researchers can elucidate the pathways impacted by the absence of DNAJC27, particularly examining changes in stress responses and protein homeostasis. Furthermore, these models facilitate the exploration of compensatory mechanisms in cellular stress responses, providing insights into novel therapeutic targets.

Scientifically, DNAJC27 knockout cell lines hold critical importance in the fields of molecular biology and medical research. They are particularly relevant in studies focused on cellular stress responses and their broader implications in health and disease. In clinical settings, understanding the role of DNAJC27 could lead to breakthroughs in treating conditions characterized by protein misfolding and aggregation.

Compared to traditional cell lines that may express variable levels of the target gene, DNAJC27 knockout cell lines provide a consistent, reproducible model devoid of the gene's influence. This specificity not only enhances the validity of experimental outcomes but also reduces confounding variables, making them a superior choice for researchers aiming for rigor in their experiments.

Investing in DNAJC27 Gene Knockout Cell Lines equates to access to high-quality, specialized models that empower researchers and clinicians to advance our understanding of genetic and molecular mechanisms. Our company prides itself on delivering meticulously crafted biological products that meet the highest standards of scientific excellence, ensuring that you have reliable tools to propel your research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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