Gene: DNAJC22
Official Full Name: DnaJ heat shock protein family (Hsp40) member C22provided by HGNC
Gene Summary: Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18203 | DNAJC22 Knockout cell line (HCT 116) | Human | DNAJC22 | 1:2~1:4 | Negative | Online Inquiry |
KO18204 | DNAJC22 Knockout cell line (HEK293) | Human | DNAJC22 | 1:3~1:6 | Negative | Online Inquiry |
KO18205 | DNAJC22 Knockout cell line (A549) | Human | DNAJC22 | 1:3~1:4 | Negative | Online Inquiry |
DNAJC22 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the function of the DNAJC22 gene, which encodes a co-chaperone protein involved in cellular stress responses and protein homeostasis. By employing CRISPR/Cas9 gene editing technology, these knockout cell lines effectively disable the DNAJC22 gene, allowing researchers to observe the resulting phenotypic and molecular changes in cellular behavior.
The primary function of these cell lines is to facilitate in-depth exploration of the roles that DNAJC22 plays in various cellular processes, particularly those related to mitochondrial function, protein folding, and the cellular response to stress. Through the elimination of DNAJC22, researchers can analyze alterations in protein aggregation, mitochondrial stress, and apoptotic pathways, offering insights into associated diseases and potential therapeutic targets.
The scientific importance of DNAJC22 Gene Knockout Cell Lines extends across research disciplines, including genetics, cell biology, and translational medicine. They are invaluable tools in investigating diseases linked to mitochondrial dysfunction, neurodegeneration, and various stress-related conditions. In clinical settings, this model can enhance drug discovery processes by providing a platform to assess the efficacy of novel compounds designed to target pathways influenced by DNAJC22.
One of the unique selling points of these knockout cell lines is the precision of the CRISPR technology used in their development, ensuring that off-target effects are minimized, and the authenticity of the knockout is validated through molecular characterizations. Additionally, these cell lines possess a robust quality assurance protocol, which enhances reproducibility and reliability, thus providing a distinct advantage over other models that may not achieve the same level of specificity.
Researchers and clinicians benefit immensely from utilizing DNAJC22 Gene Knockout Cell Lines, as they offer the potential to elucidate disease mechanisms and enhance understanding of cellular dynamics in response to genetic alterations. This enables more effective development of therapeutic strategies, ultimately leading to improvements in patient care.
Our company prides itself on excellence in biotechnological innovation and offers a comprehensive range of high-quality biological products, including custom cell lines, to cater to the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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