Gene: DNAJB14
Official Full Name: DnaJ heat shock protein family (Hsp40) member B14provided by HGNC
Gene Summary: Enables Hsp70 protein binding activity. Involved in chaperone cofactor-dependent protein refolding and protein-containing complex assembly. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18211 | DNAJB14 Knockout cell line (HeLa) | Human | DNAJB14 | 1:3~1:6 | Negative | Online Inquiry |
KO18212 | DNAJB14 Knockout cell line (HCT 116) | Human | DNAJB14 | 1:2~1:4 | Negative | Online Inquiry |
KO18213 | DNAJB14 Knockout cell line (HEK293) | Human | DNAJB14 | 1:3~1:6 | Negative | Online Inquiry |
KO18214 | DNAJB14 Knockout cell line (A549) | Human | DNAJB14 | 1:3~1:4 | Negative | Online Inquiry |
DNAJB14 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate in-depth exploration of the DNAJB14 gene's functional roles. As a member of the DnaJ/Hsp40 chaperone family, DNAJB14 is implicated in protein folding and cellular stress responses, making the knockout cell lines invaluable tools for researchers investigating critical biological processes related to proteostasis and cellular homeostasis.
These cell lines utilize advanced CRISPR-Cas9 gene-editing technology to precisely disrupt the DNAJB14 gene, thereby allowing researchers to analyze the resultant phenotypic changes and assess the gene's influence on cellular function. By removing the expression of DNAJB14, scientists can study alterations in stress response pathways, protein aggregation phenomena, and the overall impact on cellular viability under various stress conditions, including heat shock and oxidative stress.
The scientific importance of DNAJB14 Gene Knockout Cell Lines extends beyond fundamental research; they have vital applications in drug development and therapeutic interventions. For instance, understanding the dysfunctional roles of DNAJB14 in neurodegenerative diseases or cancer cells can lead to the identification of novel therapeutic targets or biomarkers.
What sets these knockout cell lines apart from alternative models is their specificity and reliability. The precise gene editing ensures consistent knockout expression, leading to reproducible results crucial for advancing scientific inquiry. Furthermore, these models provide seamless integration into various experimental frameworks, enhancing their utility across disciplines.
For researchers and clinicians focused on the intricate machinations of cellular biology, DNAJB14 Gene Knockout Cell Lines represent a significant advancement in experimental design, enabling deeper insights and novel discoveries. Our company, with its commitment to innovation and quality in biological products, provides expertly validated knockout models that empower scientific exploration and contribute to advancements in health and disease understanding.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.