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DIPK1B Knockout Cell Lines

Gene: DIPK1B

Official Full Name: divergent protein kinase domain 1Bprovided by HGNC

Gene Summary: This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown. [provided by RefSeq, Nov 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26323 DIPK1B Knockout cell line (HCT 116) Human DIPK1B 1:2~1:4 Negative Online Inquiry
KO26324 DIPK1B Knockout cell line (HEK293) Human DIPK1B 1:3~1:6 Negative Online Inquiry
KO26325 DIPK1B Knockout cell line (A549) Human DIPK1B 1:3~1:4 Negative Online Inquiry

Background

DIPK1B Gene Knockout Cell Lines are expertly engineered cellular systems designed to facilitate the study of the DIPK1B gene's functions and its various biological implications. These cell lines have been generated using targeted CRISPR-Cas9 technology to introduce precise deletions in the DIPK1B gene, allowing researchers to investigate the effects of gene disruption on cellular processes, signal transduction pathways, and metabolic functions. By creating these knockout models, scientists can effectively mimic disease states, thus providing valuable insights into pathophysiological conditions associated with aberrant DIPK1B expression.

The primary function of DIPK1B encompasses roles in cellular signaling and metabolic regulation. Its knockout leads to altered cellular behaviors, which can be quantitatively assessed using various assays, enabling the dissection of DIPK1B’s contributions to critical biological processes such as apoptosis, proliferation, differentiation, and homeostasis. Given the gene’s involvement in cellular metabolism and its emerging link to certain disease states, these knockout cell lines have significant implications both in fundamental research and in therapeutic development.

The scientific importance of DIPK1B gene knockout cell lines lies in their versatility and application in studying disorders where DIPK1B plays a pivotal role, such as obesity, metabolic syndromes, and certain cancers. Compared to traditional overexpression or pharmacological inhibition methods, knockout models provide a more accurate recapitulation of the in vivo scenarios, thereby yielding more reliable and reproducible data.

Researchers and clinicians will find value in these knockout cell lines due to their capacity to drastically enhance the understanding of the gene's role in physiological and pathological contexts. Moreover, they are an essential component for drug discovery and development pipelines aimed at targeting DIPK1B, presenting opportunities for novel therapeutic interventions.

Our company prides itself on its expertise in genetic engineering and cell line development, consistently delivering high-quality products that meet the rigorous demands of today’s scientific investigations. With these DIPK1B Gene Knockout Cell Lines, we empower researchers to advance their studies with confidence, paving the way for breakthroughs in understanding gene function and therapeutic strategies.

Please note that all services are for research use only. Not intended for any clinical use.

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