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DHX57 Knockout Cell Lines

Gene: DHX57

Official Full Name: DExH-box helicase 57provided by HGNC

Gene Summary: Enables RNA binding activity. Predicted to be involved in chromatin looping and chromatin remodeling. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23596 DHX57 Knockout cell line (HeLa) Human DHX57 1:3~1:6 Negative Online Inquiry
KO23597 DHX57 Knockout cell line (HCT 116) Human DHX57 1:2~1:4 Negative Online Inquiry
KO23598 DHX57 Knockout cell line (HEK293) Human DHX57 1:3~1:6 Negative Online Inquiry
KO23599 DHX57 Knockout cell line (A549) Human DHX57 1:3~1:4 Negative Online Inquiry

Background

DHX57 Gene Knockout Cell Lines represent a powerful tool for researchers investigating gene function and associated biological pathways. These cell lines have been meticulously engineered to lack the expression of the DHX57 gene, a member of the DEAH-box family of RNA helicases known to be involved in critical cellular processes such as RNA splicing and the regulation of gene expression. By generating these knockout models, researchers can explore the consequences of DHX57 deficiency, providing insight into its role in cancer biology, neurological disorders, and other pathophysiological conditions.

The mechanism of action lies in the targeted disruption of the DHX57 gene, leading to a complete absence of its coded protein. This allows for the elucidation of downstream effects on gene expression and cellular pathways, making it invaluable in the study of gene function. Research employing DHX57 knockout cell lines can, therefore, yield critical data regarding gene interactions and molecular signaling cascades, enhancing the understanding of various diseases at the mechanistic level.

From a scientific perspective, these cell lines hold significant importance in both basic research and clinical applications. They can serve as effective platforms for drug screening, biomarker discovery, and the development of novel therapeutic strategies targeting related pathways. The unique advantage of using DHX57 knockout cell lines over traditional methods lies in their specificity and reproducibility. By eliminating the genetic variable that the DHX57 gene introduces, results from experiments using these cell lines are often more reliable and easier to interpret compared to alternative approaches, such as transient knockdown methods that rely on RNA interference.

For researchers and clinicians alike, the ability to study the effects of the DHX57 gene in a controlled environment is a compelling proposition. The insights gained from using these cell lines can drive advances in understanding genetic diseases and ultimately contribute to the development of targeted therapies. Our company is committed to providing high-quality biological products, including the DHX57 Gene Knockout Cell Lines, thereby supporting the scientific community in their quest for transformative discoveries in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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