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DHRS13 Knockout Cell Lines

Gene: DHRS13

Official Full Name: dehydrogenase/reductase 13provided by HGNC

Gene Summary: Predicted to enable oxidoreductase activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04406 DHRS13 Knockout cell line (HeLa) Human DHRS13 1:3~1:6 Negative Online Inquiry
KO04407 DHRS13 Knockout cell line (HCT 116) Human DHRS13 1:2~1:4 Negative Online Inquiry
KO04408 DHRS13 Knockout cell line (HEK293) Human DHRS13 1:3~1:6 Negative Online Inquiry
KO04409 DHRS13 Knockout cell line (A549) Human DHRS13 1:3~1:4 Negative Online Inquiry

Background

DHRS13 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the DHRS13 gene's role in various biological processes. DHRS13 encodes a member of the short-chain dehydrogenase/reductase (SDR) family and is involved in crucial metabolic pathways, including the metabolism of steroid hormones and fatty acids. These knockout cell lines are produced using advanced CRISPR-Cas9 gene-editing technology, resulting in complete ablation of DHRS13 expression, thereby enabling researchers to observe the resultant phenotypic changes and metabolic disturbances.

The key function of these knockout cell lines lies in their utility for elucidating the biological functions and interactions of the DHRS13 gene. Researchers can investigate the effects of its absence on cellular behavior, signal transduction pathways, and metabolic profiles. By providing a controlled environment where DHRS13 is entirely non-functional, these cell lines serve as essential tools in the identification of downstream targets and pathways impacted by DHRS13, contributing to a deeper understanding of various metabolic disorders.

The scientific importance of DHRS13 knockout cell lines extends to both basic and applied research contexts. They are particularly valuable for drug discovery and toxicology studies, as they can help determine the metabolic effects of novel compounds or environmental toxins. Additionally, these models can be applied in clinical settings to enhance personalized medicine approaches by understanding individual variability in lipid metabolism and hormone regulation.

Compared to alternative products, our DHRS13 Gene Knockout Cell Lines offer rigorous validation and consistency, ensuring reliable results across experimental conditions. Unlike transient gene knockdown approaches, which may result in incomplete suppression and variability, our knockout lines provide a stable and permanent alteration of the DHRS13 locus.

For researchers and clinicians aiming to deepen their understanding of metabolic diseases and explore therapeutic avenues, these cell lines represent an invaluable resource. They empower scientists with the ability to conduct high-level mechanistic studies, ultimately contributing to the development of novel treatment strategies.

With unparalleled expertise in cellular and molecular biology, our company is dedicated to providing high-quality biological products that enhance research and clinical applications. By choosing our DHRS13 Gene Knockout Cell Lines, users invest in a scientifically robust tool that can drive innovative discoveries and therapeutic advancements in the field of metabolic research.

Please note that all services are for research use only. Not intended for any clinical use.

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