Gene: DGLUCY
Official Full Name: D-glutamate cyclaseprovided by HGNC
Gene Summary: Predicted to enable D-glutamate cyclase activity. Predicted to be involved in glutamate metabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26268 | DGLUCY Knockout cell line (HeLa) | Human | DGLUCY | 1:3~1:6 | Negative | Online Inquiry |
KO26269 | DGLUCY Knockout cell line (HCT 116) | Human | DGLUCY | 1:2~1:4 | Negative | Online Inquiry |
KO26270 | DGLUCY Knockout cell line (HEK293) | Human | DGLUCY | 1:3~1:6 | Negative | Online Inquiry |
KO26271 | DGLUCY Knockout cell line (A549) | Human | DGLUCY | 1:3~1:4 | Negative | Online Inquiry |
DGLUCY Gene Knockout Cell Lines are specialized cellular models designed for the targeted disruption of specific genes, providing invaluable tools for understanding gene function and elucidating pathways involved in various biological processes. These cell lines are generated using advanced CRISPR-Cas9 technology, which enables precise genome editing to create knockout mutations. By selectively silencing genes of interest, researchers can explore the downstream effects on cellular behavior, phenotype, and gene expression regulation, leading to breakthroughs in functional genomics and therapeutics.
The primary mechanism of DGLUCY Cell Lines involves the introduction of guide RNAs targeted to the sequence of the desired gene, coupled with the Cas9 nuclease which induces double-strand breaks in the DNA. This approach allows for disruption at the targeted locus, leading to the production of non-functional protein variants or loss of gene expression. The specific knockout of genes can significantly aid in the study of genetic diseases, drug responses, and cellular signaling pathways.
In scientific research and clinical settings, DGLUCY Gene Knockout Cell Lines serve as essential platforms for drug discovery, genetic research, and biopharmaceutical development. They facilitate the investigation of gene function in disease models, contribute to the validation of therapeutic targets, and allow for high-throughput screening of potential drug compounds. Compared to traditional gene editing methods, DGLUCY offers a more efficient, cost-effective, and reliable approach to gene knockout with a lower risk of off-target effects.
What sets DGLUCY apart from alternative products is the user-friendly design that integrates comprehensive validation, ensuring high fidelity and reproducibility in experimental applications. Researchers and clinicians can benefit from streamlined workflows, precise genetic manipulations, and access to curated control cell lines, enhancing experimental robustness.
Investing in DGLUCY Gene Knockout Cell Lines represents a strategic choice for forward-thinking researchers and clinicians focusing on innovative solutions to complex biological questions. As leaders in genetic engineering and molecular biology, our company pledges to provide rigorously validated products tailored to meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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