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DGKD Knockout Cell Lines

Gene: DGKD

Official Full Name: diacylglycerol kinase deltaprovided by HGNC

Gene Summary: This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07780 DGKD Knockout cell line (HeLa) Human DGKD 1:3~1:6 Negative Online Inquiry
KO07781 DGKD Knockout cell line (HCT 116) Human DGKD 1:2~1:4 Negative Online Inquiry
KO07782 DGKD Knockout cell line (HEK293) Human DGKD 1:3~1:6 Negative Online Inquiry
KO07783 DGKD Knockout cell line (A549) Human DGKD 1:3~1:4 Negative Online Inquiry

Background

DGKD Gene Knockout Cell Lines are specially engineered cell lines where the diacylglycerol kinase delta (DGKD) gene has been completely disrupted. This gene is critical for regulating lipid signaling pathways and cellular responses to various stimuli. By knocking out the DGKD gene, researchers can study the downstream effects on diacylglycerol metabolism, which plays a pivotal role in cellular functions such as proliferation, differentiation, and apoptosis.

These cell lines function by providing an ideal platform for investigating the biological roles of DGKD in health and disease. Researchers can utilize these knockout models to elucidate the mechanisms by which altered DGKD expression may influence diseases such as cancer, metabolic disorders, and cardiovascular diseases. The absence of DGKD allows for a clear analysis of diacylglycerol's role in cell signaling, enabling scientists to explore new therapeutic strategies.

The scientific importance of DGKD Gene Knockout Cell Lines cannot be overstated. They offer invaluable insight into lipid signaling mechanisms, advancing our understanding of cellular metabolism in both research and clinical contexts. Additionally, these models significantly contribute to drug discovery efforts by providing a reliable basis for evaluating therapeutic interventions targeting lipid metabolism.

One of the unique advantages of using DGKD Gene Knockout Cell Lines is their specificity and reliability compared to conventional knockdown approaches using RNA interference, which may yield incomplete or transient effects. The complete knockout ensures a more consistent expression profile, allowing for robust replicability in experiments. Furthermore, these cell lines streamline the process of studying DGKD-related pathways by minimizing confounding variables.

Researchers and clinicians value this product not only for its ability to unlock new avenues of research but also for its potential applications in therapeutic development. By employing the DGKD Gene Knockout Cell Lines, they can make significant strides in understanding complex cellular processes and exploring innovative treatment options.

Our company is dedicated to advancing scientific research by providing high-quality biological products that empower researchers and clinicians alike. With a focus on precision and reliability, our offerings, including the DGKD Gene Knockout Cell Lines, are designed to support groundbreaking discoveries in the field of molecular biology and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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