Gene: DEPDC1B
Official Full Name: DEP domain containing 1Bprovided by HGNC
Gene Summary: Predicted to enable GTPase activator activity. Involved in cell migration and positive regulation of Wnt signaling pathway. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05841 | DEPDC1B Knockout cell line (HeLa) | Human | DEPDC1B | 1:3~1:6 | Negative | Online Inquiry |
KO05842 | DEPDC1B Knockout cell line (HCT 116) | Human | DEPDC1B | 1:2~1:4 | Negative | Online Inquiry |
KO05843 | DEPDC1B Knockout cell line (HEK293) | Human | DEPDC1B | 1:3~1:6 | Negative | Online Inquiry |
KO05844 | DEPDC1B Knockout cell line (A549) | Human | DEPDC1B | 1:3~1:4 | Negative | Online Inquiry |
DEPDC1B Gene Knockout Cell Lines are genetically engineered cell lines in which the DEPDC1B gene has been disabled, creating a powerful tool for researchers to study the gene's role in cellular processes such as growth, differentiation, and disease pathology. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines facilitate the precise deletion of the DEPDC1B gene, allowing scientists to explore the functional consequences of its absence in various biological contexts.
The primary mechanism of action in DEPDC1B Gene Knockout Cell Lines revolves around the disruption of the DEPDC1B gene expression, leading to altered signaling pathways associated with cancer progression, immune response, and cellular metabolism. This presents a unique opportunity to dissect the specific roles of DEPDC1B in tumor biology and its potential implications in therapeutic interventions, making these cell lines instrumental for both fundamental and translational research.
From a scientific perspective, the relevance of DEPDC1B in various cancers suggests significant applications in drug discovery, biomarker identification, and the development of targeted therapies. Researchers can utilize these knockout lines to validate hypotheses regarding the gene’s involvement in malignancy and to screen pharmaceutical compounds that modulate its activity.
One of the unique advantages of our DEPDC1B Gene Knockout Cell Lines lies in their high specificity and reproducibility, which surpass other conventional methods such as RNA interference. This high efficiency enables clearer interpretations of gene function and greater confidence in experimental outcomes. In addition, our cell lines are rigorously characterized, ensuring that researchers receive reliable and consistent materials for their work.
For researchers and clinicians focused on advancing cancer biology and developing novel therapeutics, these cell lines represent an invaluable resource. They not only streamline the research process but also enhance the potential for innovative discoveries that can lead to improved patient outcomes.
Our company specializes in the production of high-quality, specialized cell lines, backed by years of expertise in genetic engineering. We are dedicated to supporting the scientific community with products that enhance research capabilities and contribute to the advancement of biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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