Gene: DENND4C
Official Full Name: DENN domain containing 4Cprovided by HGNC
Gene Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus; protein localization to plasma membrane; and regulation of Rab protein signal transduction. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18324 | DENND4C Knockout cell line (HeLa) | Human | DENND4C | 1:3~1:6 | Negative | Online Inquiry |
KO18325 | DENND4C Knockout cell line (HCT 116) | Human | DENND4C | 1:2~1:4 | Negative | Online Inquiry |
KO18326 | DENND4C Knockout cell line (HEK293) | Human | DENND4C | 1:3~1:6 | Negative | Online Inquiry |
KO18327 | DENND4C Knockout cell line (A549) | Human | DENND4C | 1:3~1:4 | Negative | Online Inquiry |
DENND4C Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the DENND4C gene, which is implicated in various cellular processes such as endocytosis and intracellular cargo trafficking. These knockout cell lines are crucial for researchers aiming to elucidate the biological functions of DENND4C, particularly its role in modulating signaling pathways and cellular dynamics.
The primary function of DENND4C Gene Knockout Cell Lines involves examining the consequences of the absence of this specific gene. By utilizing CRISPR-Cas9 technology, these cell lines facilitate the study of gene function, allowing researchers to investigate the downstream effects on cellular processes. This includes analyzing how DENND4C influences cellular signaling pathways, protein interactions, and the overall cellular phenotype.
In the realm of scientific research and clinical settings, these knockout cell lines serve as invaluable tools for understanding diseases where DENND4C is involved. They are particularly relevant in studies related to neurobiology, cancer, and metabolic disorders. Their use can lead to the identification of novel therapeutic targets and the development of innovative treatment strategies.
What sets DENND4C Gene Knockout Cell Lines apart from alternative models is their precision and reliability. Unlike conventional cell lines that may express varying levels of the target gene, these knockout lines provide an unambiguous insight into the gene's function. Additionally, they can be employed in high-throughput screening assays, thus accelerating the pace of research and discovery.
For researchers and clinicians, the value of DENND4C Gene Knockout Cell Lines lies in their ability to drive breakthroughs in understanding complex biological systems and disease mechanisms. By providing a clear genetic context for experiments, they enhance the precision of research outcomes, leading to more informed conclusions and potential therapeutic advancements.
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Please note that all services are for research use only. Not intended for any clinical use.
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