Gene: DDX60
Official Full Name: DExD/H-box helicase 60provided by HGNC
Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular procsses involving RNA binding and alteration of RNA secondary structure. This gene encodes a DEXD/H box RNA helicase that functions as an antiviral factor and promotes RIG-I-like receptor-mediated signaling. [provided by RefSeq, Apr 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18348 | DDX60 Knockout cell line (HeLa) | Human | DDX60 | 1:3~1:6 | Negative | Online Inquiry |
KO18349 | DDX60 Knockout cell line (HCT 116) | Human | DDX60 | 1:2~1:4 | Negative | Online Inquiry |
KO18350 | DDX60 Knockout cell line (A549) | Human | DDX60 | 1:3~1:4 | Negative | Online Inquiry |
DDX60 Gene Knockout Cell Lines are specialized cell lines that have undergone precise genetic modification to eliminate the DDX60 gene, which encodes for a member of the DEAD-box RNA helicase family. This product is fundamentally significant for researchers investigating the roles of DDX60 in various cellular processes, including RNA metabolism, antiviral responses, and immune signaling pathways. By providing a reliable platform for the study of DDX60 function, these knockout cell lines facilitate in-depth analyses of gene function and the molecular mechanisms underlying disease, particularly in contexts related to viral infection and immune dysregulation.
The key mechanism by which DDX60 affects cellular function is through its involvement in the recognition and unwinding of complex RNA structures, which is crucial for the activation of innate immune responses to viral pathogens. By utilizing DDX60 knockout cell lines, researchers can create precise in vitro models that allow them to elucidate the gene's specific roles and assess the biological consequences of its loss. This model serves as a powerful tool in the discovery of novel therapeutic targets and the development of antiviral strategies.
In comparison to other gene knockout models, DDX60 Gene Knockout Cell Lines offer several advantages including a well-characterized genetic background, reliable reproducibility, and the ability to use them in various cellular assays. They are equipped to enable high-throughput screening and characterization of potential drugs that modulate the activity of RNA helicases, making them an invaluable asset in the realm of drug discovery.
The value of these cell lines extends beyond research laboratories into clinical settings, where understanding DDX60's role can pave the way for innovative approaches in the treatment of diseases linked to dysregulated immune responses. Whether for elucidating basic biological processes or developing next-generation therapeutics, DDX60 Gene Knockout Cell Lines empower scientists and clinicians with the tools necessary to drive discovery forward.
With years of experience and specialization in developing advanced biological products, our company is committed to providing researchers with high-quality, scientifically robust tools that foster innovation and accelerate breakthrough findings in molecular biology and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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