Gene: DDRGK1
Official Full Name: DDRGK domain containing 1provided by HGNC
Gene Summary: The protein encoded by this gene interacts with components of the ubiquitin fold modifier 1 conjugation pathway and helps prevent apoptosis in ER-stressed secretory tissues. In addition, the encoded protein regulates nuclear factor-κB activity. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18363 | DDRGK1 Knockout cell line (HeLa) | Human | DDRGK1 | 1:3~1:6 | Negative | Online Inquiry |
KO18364 | DDRGK1 Knockout cell line (HCT 116) | Human | DDRGK1 | 1:2~1:4 | Negative | Online Inquiry |
KO18365 | DDRGK1 Knockout cell line (HEK293) | Human | DDRGK1 | 1:3~1:6 | Negative | Online Inquiry |
KO18366 | DDRGK1 Knockout cell line (A549) | Human | DDRGK1 | 1:3~1:4 | Negative | Online Inquiry |
DDRGK1 Gene Knockout Cell Lines are genetically modified cell lines in which the DDRGK1 gene, known for its role in cellular responses to stress and signaling pathways, has been inactivated or "knocked out." This innovative product allows researchers to investigate the functional implications of lacking DDRGK1 in various cellular contexts. The functionality of these cell lines is grounded in the precise CRISPR-Cas9 gene editing technique, which enables targeted mutations and eliminates the gene’s expression, facilitating studies on how DDRGK1 influences cellular behavior, differentiation, and response to external stimuli.
The scientific importance of DDRGK1 Gene Knockout Cell Lines lies in their applications in both basic and translational research. They help elucidate the mechanisms underlying cellular repair processes and could lead to a better understanding of disorders linked to impaired DDRGK1 function, such as cancer and neurodegenerative diseases. By providing a clear model for studying DDRGK1’s role in various biological phenomena, these cell lines become invaluable tools for drug discovery and development, allowing researchers to screen for potential therapeutics that may interact with this critical gene.
Compared to conventional knockdown strategies, such as RNA interference, these knockout cell lines offer the advantage of complete gene inactivation, leading to more definitive insights into gene function. Furthermore, the robustness and reproducibility of CRISPR-Cas9 technologies ensure high-quality results that researchers can depend upon.
For researchers and clinicians aiming to deepen their understanding of DDRGK1 and its implications in health and disease, DDRGK1 Gene Knockout Cell Lines are essential. Their ability to provide a clear genetic context allows for precise investigations, paving the way for novel therapeutic strategies. Our company specializes in cutting-edge genetic engineering and cellular technologies, ensuring that our products are validated, well-characterized, and tailored to meet the dynamic needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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