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DDIT4L Knockout Cell Lines

Gene: DDIT4L

Official Full Name: DNA damage inducible transcript 4 likeprovided by HGNC

Gene Summary: Predicted to be involved in negative regulation of signal transduction. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30631 DDIT4L Knockout cell line (HCT 116) Human DDIT4L 1:2~1:4 Negative Online Inquiry
KO30632 DDIT4L Knockout cell line (A549) Human DDIT4L 1:3~1:4 Negative Online Inquiry

Background

DDIT4L Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, engineered to provide insights into the functions of the DDIT4L gene, which is crucial in regulating cellular responses to stress and metabolic changes. These cell lines are created using advanced CRISPR-Cas9 technology, enabling precise deletion of the DDIT4L gene, thus facilitating the study of its downstream effects in various biological pathways.

The primary function of DDIT4L Gene Knockout Cell Lines lies in their utility for evaluating the biological ramifications of DDIT4L loss. By comparing these knockout cells with wild-type controls, researchers can elucidate the gene's role in processes such as cell growth, apoptosis, and metabolism. The precise mechanisms of action involve modulation of the mTOR signaling pathway, which is significantly influenced by DDIT4L, allowing for a deeper understanding of disease mechanisms and potential therapeutic targets.

The scientific importance of these cell lines is underscored by their applications in both research and clinical settings, particularly in studying metabolic disorders and cancer biology. They provide a unique experimental platform for drug discovery and testing, as well as for elucidating the physiological roles of DDIT4L in health and disease. Researchers can utilize these models to explore therapeutic strategies aimed at diseases where DDIT4L may play a role, enhancing the translational potential of their findings.

Distinct advantages of DDIT4L Gene Knockout Cell Lines over alternative models include their high specificity and reproducibility, reducing off-target effects that can compromise experimental validity. Additionally, these cell lines are generated with rigorous quality standards, ensuring dependable results that researchers can trust.

For clinicians and researchers alike, the value of DDIT4L Gene Knockout Cell Lines is evident in their ability to bridge the gap between basic science and clinical applications, offering new avenues for understanding complex biological systems and developing novel therapeutics. Our company specializes in producing high-quality biological research tools, with a commitment to advancing scientific discovery through innovation and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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