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CYP4X1 Knockout Cell Lines

Gene: CYP4X1

Official Full Name: cytochrome P450 family 4 subfamily X member 1provided by HGNC

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18443 CYP4X1 Knockout cell line (HEK293) Human CYP4X1 1:3~1:6 Negative Online Inquiry

Background

CYP4X1 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to lack the CYP4X1 gene, which encodes for a cytochrome P450 enzyme known to play critical roles in metabolizing various endogenous and exogenous compounds. This product allows researchers to investigate the impact of CYP4X1 absence on various biological processes, drug metabolism, and pharmacokinetics.

These cell lines function as powerful tools for elucidating the specific signaling pathways and metabolic routes influenced by CYP4X1. By studying the gene knockout variants, scientists can observe changes in substrate metabolism, alterations in drug sensitivity, and other phenotypic traits that would not be evident in wild-type cells. The mechanism underlying this is facilitated through the disruption of enzymatic activity normally offered by CYP4X1, providing a clearer understanding of its physiological and pathological roles.

The scientific importance of CYP4X1 Gene Knockout Cell Lines cannot be overstated, particularly in pharmacological research and toxicology studies. They serve as invaluable assets in drug development processes, enabling a more precise assessment of drug efficacy and safety. Furthermore, these cell models can help unravel the contributions of CYP4X1 to various diseases, making them relevant in both preclinical and clinical research contexts.

What sets our CYP4X1 Gene Knockout Cell Lines apart from other available products is the rigorous validation and characterization every line undergoes, ensuring optimal performance and reproducibility in experiments. Additionally, our product is compatible with common cell culture protocols and can be tailored to meet specific research needs, paving the way for streamlined integration into existing workflows.

In summary, CYP4X1 Gene Knockout Cell Lines offer researchers and clinicians unparalleled insights into the metabolic functions of cytochrome P450 enzymes, opening avenues for novel therapeutic developments. Backed by our company's extensive expertise in providing high-quality biological products, we remain committed to supporting your research endeavors through innovative and reliable cellular models that enhance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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