Gene: CYP2U1
Official Full Name: cytochrome P450 family 2 subfamily U member 1provided by HGNC
Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30830 | CYP2U1 Knockout cell line (HeLa) | Human | CYP2U1 | 1:3~1:6 | Negative | Online Inquiry |
KO30831 | CYP2U1 Knockout cell line (HCT 116) | Human | CYP2U1 | 1:2~1:4 | Negative | Online Inquiry |
KO30832 | CYP2U1 Knockout cell line (HEK293) | Human | CYP2U1 | 1:3~1:6 | Negative | Online Inquiry |
KO30833 | CYP2U1 Knockout cell line (A549) | Human | CYP2U1 | 1:3~1:4 | Negative | Online Inquiry |
CYP2U1 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the CYP2U1 gene, a member of the cytochrome P450 family traditionally associated with drug metabolism and the oxidative metabolism of various substrates. This product provides a powerful tool for researchers investigating the role of CYP2U1 in metabolic pathways, pharmacogenomics, and toxicology, facilitating the study of drug interactions and individual responses to medications.
The primary function of CYP2U1 is to facilitate the metabolism of endogenous and exogenous compounds through monooxygenation processes. By knocking out this gene, researchers can observe the resultant physiological effects and metabolic shifts, thus gaining insights into the gene's specific roles within cellular functions. Furthermore, these cell lines enable the exploration of CYP2U1’s impact on lipid metabolism, neurological development, and potential implications in various diseases.
Scientifically, CYP2U1 Gene Knockout Cell Lines are crucial in preclinical research, advancing our understanding of drug disposition and the potential for adverse drug reactions. Their application spans diverse fields, from pharmacology and toxicology to personalized medicine, allowing for more accurate models of human disease that can lead to improved therapeutic strategies.
Compared to other knockout systems or cell lines expressing the CYP2U1 gene, these specialized cell lines offer researchers a clear advantage by eliminating confounding variables, thus providing more reliable data. Their unique capability to mimic human metabolic processes makes them an invaluable resource for drug discovery and disease modeling.
For researchers and clinicians looking to deepen their understanding of cytochrome P450 functionalities and develop more effective therapeutic regimes, these knockout cell lines present a pivotal resource. By leveraging our expertise in genetic engineering and cell line development, we stand at the forefront of innovative biological products that empower the scientific community to make significant advancements in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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