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CYB5R1 Knockout Cell Lines

Gene: CYB5R1

Official Full Name: cytochrome b5 reductase 1provided by HGNC

Gene Summary: Predicted to enable FAD binding activity. Predicted to be involved in bicarbonate transport. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22255 CYB5R1 Knockout cell line (HeLa) Human CYB5R1 1:3~1:6 Negative Online Inquiry
KO22256 CYB5R1 Knockout cell line (HCT 116) Human CYB5R1 1:2~1:4 Negative Online Inquiry
KO22257 CYB5R1 Knockout cell line (HEK293) Human CYB5R1 1:3~1:6 Negative Online Inquiry
KO22258 CYB5R1 Knockout cell line (A549) Human CYB5R1 1:3~1:4 Negative Online Inquiry

Background

CYB5R1 Gene Knockout Cell Lines are genetically engineered cellular models that lack the cytochrome b5 reductase 1 gene (CYB5R1), which encodes an enzyme important in various cellular processes, including metabolism and electron transfer in redox reactions. These knockout cell lines serve as invaluable tools for researchers seeking to unravel the functional roles of CYB5R1 in normal physiology and disease states.

The primary mechanism of CYB5R1 involves the reduction of methemoglobin to hemoglobin and the facilitation of fatty acid desaturation; these functions contribute to maintaining cellular homeostasis. By studying CYB5R1 knockout cell lines, researchers can better understand the biochemical pathways that are disrupted in conditions such as cardiovascular disease, metabolic disorders, and certain types of cancer, thereby elucidating potential therapeutic targets.

The scientific importance of these cell lines cannot be overstated. They enable detailed investigations in both basic and translational research by providing insight into the physiological and pathological roles of the CYB5R1 enzyme. Moreover, their application in drug development may optimize therapies targeting metabolic pathways influenced by this enzyme, leading to innovative treatment options.

Distinct from alternative cellular models, CYB5R1 Gene Knockout Cell Lines offer a high degree of specificity for studying gene function without confounding effects from the normal gene expression. Researchers benefit from the reproducibility and consistency these cell lines provide, ensuring robust experimental results.

For both researchers and clinicians, the value of these knockout cell lines lies in their potential to drive the discovery of novel interventions. With a precise genetic background, they streamline experimental protocols, enhancing the efficiency of research endeavors.

At our company, we are committed to advancing scientific knowledge through the provision of high-quality biological products. Our expertise in genetic engineering and extensive experience in cellular biology equips us to offer you funding and support for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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