Gene: CXXC1
Official Full Name: CXXC finger protein 1provided by HGNC
Gene Summary: This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26739 | CXXC1 Knockout cell line (HeLa) | Human | CXXC1 | 1:3~1:6 | Negative | Online Inquiry |
KO26740 | CXXC1 Knockout cell line (HCT 116) | Human | CXXC1 | 1:2~1:4 | Negative | Online Inquiry |
KO26741 | CXXC1 Knockout cell line (HEK293) | Human | CXXC1 | 1:3~1:6 | Negative | Online Inquiry |
CXXC1 Gene Knockout Cell Lines are specialized cellular models in which the CXXC1 gene has been functionally inactivated through targeted gene editing technologies such as CRISPR-Cas9. This product allows researchers to explore the phenotype and functional implications of silencing this gene, which is believed to play a critical role in cellular regulation, epigenetic control, and developmental processes. The generated cell lines provide a powerful tool for dissecting the biological functions mediated by CXXC1, enabling investigations into its involvement in various physiological and pathological contexts.
The key mechanism of action involves the precise knockout of the CXXC1 gene, which results in a loss of its encoded protein and subsequent alteration of associated signaling pathways. This disruption allows scientists to observe changes in cell behavior, gene expression, and response to external stimuli, thereby elucidating the role of CXXC1 in gene regulation and potential oncogenic pathways.
The scientific importance of CXXC1 knockout cell lines spans multiple applications, including gene function studies, modeling diseases, and drug discovery. By utilizing these cell lines, researchers can elucidate the downstream effects of CXXC1 loss, exploring its relevance in cancer biology, neurodevelopmental disorders, and autoimmune diseases, among others.
Compared to other available gene knockout models, CXXC1 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility, backed by robust validation processes ensuring editing efficiency. Moreover, they come with detailed characterization data, which adds to their reliability in experimental setups.
For researchers and clinicians, incorporating these cell lines into experimental protocols can accelerate the discovery of novel therapeutic targets and enhance the understanding of disease mechanisms, ultimately leading to improved healthcare outcomes.
With a strong foundation in genetic engineering and a commitment to advancing research tools, our company provides high-quality biological products designed to empower scientific inquiry and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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