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CTSA Knockout Cell Lines

Gene: CTSA

Official Full Name: cathepsin Aprovided by HGNC

Gene Summary: This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35958 CTSA Knockout cell line (HeLa) Human CTSA 1:3~1:6 Negative Online Inquiry
KO35959 CTSA Knockout cell line (HCT 116) Human CTSA 1:2~1:4 Negative Online Inquiry
KO35960 CTSA Knockout cell line (HEK293) Human CTSA 1:3~1:6 Negative Online Inquiry
KO35961 CTSA Knockout cell line (A549) Human CTSA 1:3~1:4 Negative Online Inquiry

Background

CTSA Gene Knockout Cell Lines are genetically engineered cell models that feature specific gene deletions aimed at providing insight into gene function and mechanisms of disease. These lines are constructed using advanced CRISPR-Cas9 technology, which allows for precise and efficient gene editing. As a result, researchers can effectively study the phenotypic and molecular consequences of gene loss in various cellular contexts, thus unraveling critical pathways involved in cellular processes.

The core functionality of CTSA Gene Knockout Cell Lines lies in their ability to facilitate functional genomics studies. By generating cell lines deficient in specific genes, researchers can systematically investigate changes in cell behavior, signaling pathways, and metabolic functions. This knockout technology enables the investigation of loss-of-function mutations relevant to various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. Additionally, these cell lines serve as valuable tools for drug development, allowing researchers to evaluate the therapeutic efficacy of new compounds in genetically defined backgrounds.

The scientific significance of CTSA Gene Knockout Cell Lines extends into both basic research and clinical applications. They provide a powerful platform for screening potential drug targets and understanding genetic contributions to disease phenotypes, especially in personalized medicine approaches. Compared to traditional methods of generating knockout models, our CTSA cell lines offer a streamlined process with an unprecedented level of specificity and efficiency. This ensures that researchers spend less time and resources on creating models, facilitating faster experimental timelines and accelerated discovery processes.

What sets CTSA Gene Knockout Cell Lines apart from alternatives is their ready-to-use status, enabling researchers to quickly implement them into their studies without the need for extensive background validation. Our products are standardized for optimal performance and reproducibility, ensuring that scientists can trust their results.

For researchers, clinicians, and pharmaceutical developers seeking to unlock the intricacies of gene function and disease mechanisms, CTSA Gene Knockout Cell Lines represent an invaluable resource. By providing a robust, user-friendly product backed by rigorous scientific research, our company stands as a leader in the field of genetic engineering and cell biology.

Please note that all services are for research use only. Not intended for any clinical use.

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