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CTDSPL Knockout Cell Lines

Gene: CTDSPL

Official Full Name: CTD small phosphatase likeprovided by HGNC

Gene Summary: Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of G1/S transition of mitotic cell cycle and negative regulation of protein phosphorylation. Located in extracellular exosome. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32123 CTDSPL Knockout cell line (HeLa) Human CTDSPL 1:3~1:6 Negative Online Inquiry
KO32124 CTDSPL Knockout cell line (HCT 116) Human CTDSPL 1:2~1:4 Negative Online Inquiry
KO32125 CTDSPL Knockout cell line (HEK293) Human CTDSPL 1:3~1:6 Negative Online Inquiry
KO32126 CTDSPL Knockout cell line (A549) Human CTDSPL 1:3~1:4 Negative Online Inquiry

Background

CTDSPL Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene disruption of the CTDSPL gene, a critical player in various cellular processes including signal transduction and apoptosis regulation. These cell lines are established using cutting-edge CRISPR/Cas9 genome-editing technology, providing a reliable platform for studying the functional outcomes of gene loss.

The primary function of CTDSPL Gene Knockout Cell Lines allows researchers to elucidate the biological roles of CTDSPL in cellular pathways. The knockout phenotype facilitates investigation into gene interactions, protein expression, and downstream effects in relevant biological contexts. By comparing these knockout cell lines to wild-type controls, scientists can gain insights into the mechanistic basis of disease, including its implications in cancer biology, neurodegenerative disorders, and developmental abnormalities.

The scientific importance of these cell lines lies in their wide-ranging applications in both basic and translational research. Through the study of CTDSPL-deficient cells, researchers can explore novel therapeutic targets, validate drug effects, and assess gene-environment interactions, ultimately enhancing our understanding of complex pathologies.

Compared to alternative models, CTDSPL Gene Knockout Cell Lines offer significant advantages. They provide a controlled genetic background, minimize off-target effects, and yield reproducible results, all of which are essential for high-quality scientific investigations. Furthermore, these cell lines are compatible with high-throughput screening, broadening their utility in pharmacological studies.

For researchers and clinicians alike, the CTDSPL Gene Knockout Cell Lines represent an invaluable tool to propel scientific discovery. Their precision and reliability make them a preferred choice in the realm of genetic studies, fostering innovation in therapeutic development and disease understanding.

Our company is committed to advancing life sciences research by providing high-quality biological products. With a focus on innovation and excellence, we deliver tools that empower researchers to push the boundaries of scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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