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CTDSP1 Knockout Cell Lines

Gene: CTDSP1

Official Full Name: CTD small phosphatase 1provided by HGNC

Gene Summary: This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18492 CTDSP1 Knockout cell line (HeLa) Human CTDSP1 1:3~1:6 Negative Online Inquiry
KO18493 CTDSP1 Knockout cell line (HCT 116) Human CTDSP1 1:2~1:4 Negative Online Inquiry
KO18494 CTDSP1 Knockout cell line (HEK293) Human CTDSP1 1:3~1:6 Negative Online Inquiry
KO18495 CTDSP1 Knockout cell line (A549) Human CTDSP1 1:3~1:4 Negative Online Inquiry

Background

CTDSP1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to lack the expression of the CTDSP1 gene, a crucial player in multiple cellular processes, including RNA processing and transcriptional regulation. This innovative tool allows researchers to investigate the biological implications of CTDSP1 deficiency and to elucidate its role in various diseases, particularly cancer and neurodegeneration.

The primary mechanism of the CTDSP1 Gene Knockout Cell Lines revolves around the targeted disruption of the CTDSP1 gene using advanced CRISPR-Cas9 technology. This approach ensures precise and efficient gene modification, resulting in the creation of cell lines that exhibit a complete lack of functional CTDSP1 protein. By providing a reliable platform for studying gene function, these knockout cell lines facilitate the investigation of downstream signaling pathways and gene interactions that may be altered due to CTDSP1 loss.

The scientific significance of CTDSP1 knockout models extends to their applications in both research and clinical settings. They serve as invaluable tools for understanding the molecular underpinnings of diseases and can be employed in drug discovery processes, functional genomics, and therapeutic development. Furthermore, these cell lines enable pharmacological testing and the evaluation of gene-environment interactions in disease models.

One of the primary advantages of CTDSP1 Gene Knockout Cell Lines is their ability to generate reproducible and consistent results, addressing the variability often associated with other approaches. Additionally, the use of validated knockout models enhances the credibility of experimental findings, giving researchers increased confidence in their data. Compared to alternative cell lines that may maintain residual CTDSP1 activity, our product ensures a complete functional knockout, allowing for a more comprehensive exploration of gene function.

For researchers and clinicians alike, the CTDSP1 Gene Knockout Cell Lines provide a distinctive advantage in dissecting the complexities of gene function in health and disease. By utilizing this product, users can accelerate their research endeavors, contributing to an improved understanding of cellular mechanisms and the potential for innovative therapeutic strategies.

Our company is committed to providing cutting-edge genetic tools and biological products tailored to meet the needs of the scientific community. With extensive expertise in gene editing technologies and a focus on quality, we ensure that our offerings empower researchers to pursue their projects with confidence and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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